Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
| ISSN: |
0012-1606
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| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
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| Topics: |
Biology
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798290761081421824 |
|---|---|
| autor | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| autorsonst | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| book_url | http://dx.doi.org/10.1006/dbio.1993.1299 |
| datenlieferant | nat_lic_papers |
| fussnote | We describe major transitions in the type and modification of chromatin-associated proteins during the early development of Xenopus laevis. Histone H4 is stored in the diacetylated form in the egg and is progressively deacetylated during normal development. If histone deacetylases are inhibited with sodium butyrate, hyperacetylated histone H4 only accumulates after the mid-blastula transition. The type of linker histone in chromatin also changes during embryogenesis, from predominantly the B4 protein at the mid-blastula transition to predominantly histone H1 at the end of gastrulation. These transitions in chromatin composition correlate with major changes in the replicative and transcriptional activity of embryonic nuclei. |
| hauptsatz | hsatz_simple |
| identnr | NLZ183609603 |
| issn | 0012-1606 |
| journal_name | Developmental Biology |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 160 (1993), S. 214-227 |
| search_space | articles |
| shingle_author_1 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| shingle_author_2 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| shingle_author_3 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| shingle_author_4 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. |
| shingle_catch_all_1 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type 0012-1606 00121606 Elsevier |
| shingle_catch_all_2 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type 0012-1606 00121606 Elsevier |
| shingle_catch_all_3 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type 0012-1606 00121606 Elsevier |
| shingle_catch_all_4 | Dimitrov, S. Almouzni, G. Dasso, M. Wolffe, A.P. Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type 0012-1606 00121606 Elsevier |
| shingle_title_1 | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type |
| shingle_title_2 | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type |
| shingle_title_3 | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type |
| shingle_title_4 | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:21:52.083Z |
| titel | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type |
| titel_suche | Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type We describe major transitions in the type and modification of chromatin-associated proteins during the early development of Xenopus laevis. Histone H4 is stored in the diacetylated form in the egg and is progressively deacetylated during normal development. If histone deacetylases are inhibited with sodium butyrate, hyperacetylated histone H4 only accumulates after the mid-blastula transition. The type of linker histone in chromatin also changes during embryogenesis, from predominantly the B4 protein at the mid-blastula transition to predominantly histone H1 at the end of gastrulation. These transitions in chromatin composition correlate with major changes in the replicative and transcriptional activity of embryonic nuclei. |
| topic | W |
| uid | nat_lic_papers_NLZ183609603 |