Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type

Dimitrov, S. ; Almouzni, G. ; Dasso, M. ; Wolffe, A.P.

Amsterdam : Elsevier
ISSN:
0012-1606
Source:
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
Topics:
Biology
Type of Medium:
Electronic Resource
URL:
_version_ 1798290761081421824
autor Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
autorsonst Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
book_url http://dx.doi.org/10.1006/dbio.1993.1299
datenlieferant nat_lic_papers
fussnote We describe major transitions in the type and modification of chromatin-associated proteins during the early development of Xenopus laevis. Histone H4 is stored in the diacetylated form in the egg and is progressively deacetylated during normal development. If histone deacetylases are inhibited with sodium butyrate, hyperacetylated histone H4 only accumulates after the mid-blastula transition. The type of linker histone in chromatin also changes during embryogenesis, from predominantly the B4 protein at the mid-blastula transition to predominantly histone H1 at the end of gastrulation. These transitions in chromatin composition correlate with major changes in the replicative and transcriptional activity of embryonic nuclei.
hauptsatz hsatz_simple
identnr NLZ183609603
issn 0012-1606
journal_name Developmental Biology
materialart 1
package_name Elsevier
publikationsort Amsterdam
publisher Elsevier
reference 160 (1993), S. 214-227
search_space articles
shingle_author_1 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
shingle_author_2 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
shingle_author_3 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
shingle_author_4 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
shingle_catch_all_1 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
0012-1606
00121606
Elsevier
shingle_catch_all_2 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
0012-1606
00121606
Elsevier
shingle_catch_all_3 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
0012-1606
00121606
Elsevier
shingle_catch_all_4 Dimitrov, S.
Almouzni, G.
Dasso, M.
Wolffe, A.P.
Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
0012-1606
00121606
Elsevier
shingle_title_1 Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
shingle_title_2 Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
shingle_title_3 Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
shingle_title_4 Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
fhp
source_archive Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
timestamp 2024-05-06T08:21:52.083Z
titel Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
titel_suche Chromatin Transitions during Early Xenopus Embryogenesis: Changes in Histone H4 Acetylation and in Linker Histone Type
We describe major transitions in the type and modification of chromatin-associated proteins during the early development of Xenopus laevis. Histone H4 is stored in the diacetylated form in the egg and is progressively deacetylated during normal development. If histone deacetylases are inhibited with sodium butyrate, hyperacetylated histone H4 only accumulates after the mid-blastula transition. The type of linker histone in chromatin also changes during embryogenesis, from predominantly the B4 protein at the mid-blastula transition to predominantly histone H1 at the end of gastrulation. These transitions in chromatin composition correlate with major changes in the replicative and transcriptional activity of embryonic nuclei.
topic W
uid nat_lic_papers_NLZ183609603