Expression and cDNA Cloning of Human HMGI-C Phosphoprotein
Patel, U.A. ; Bandiera, A. ; Manfioletti, G. ; Giancotti, V. ; Chau, K.Y. ; Cranerobinson, C.
Amsterdam : Elsevier
Amsterdam : Elsevier
| ISSN: |
0006-291X
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|---|---|
| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
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| Topics: |
Biology
Chemistry and Pharmacology
Physics
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798292264550662144 |
|---|---|
| autor | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| autorsonst | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| book_url | http://dx.doi.org/10.1006/bbrc.1994.1669 |
| datenlieferant | nat_lic_papers |
| fussnote | The HMGI family contains three members: I, Y and I-C. HMGI and HMGY are alternative splicings of the same gene and are essential transcription factors at several genetic loci. HMGI-C is transcribed from a different gene and is observed only in highly transformed cells. This work shows that human I-C is present in a more restricted range of cell types than I/Y and is absent from hemopoietic cells, as noted for mouse I-C. However, high expression in a human hepatoma line allowed the cloning of the cDNA and 812 bp of 5'-untranslated, 330 bp of coding and 58 bp of 3'-untranslated DNA were sequenced. The open reading frame showed 4 amino acid substitutions and one additional amino acid when compared to mouse I-C, none of them in the basic DNA binding motifs. |
| hauptsatz | hsatz_simple |
| identnr | NLZ183479327 |
| issn | 0006-291X |
| journal_name | Biochemical and Biophysical Research Communications |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 201 (1994), S. 63-70 |
| search_space | articles |
| shingle_author_1 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| shingle_author_2 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| shingle_author_3 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| shingle_author_4 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. |
| shingle_catch_all_1 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. Expression and cDNA Cloning of Human HMGI-C Phosphoprotein 0006-291X 0006291X Elsevier |
| shingle_catch_all_2 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. Expression and cDNA Cloning of Human HMGI-C Phosphoprotein 0006-291X 0006291X Elsevier |
| shingle_catch_all_3 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. Expression and cDNA Cloning of Human HMGI-C Phosphoprotein 0006-291X 0006291X Elsevier |
| shingle_catch_all_4 | Patel, U.A. Bandiera, A. Manfioletti, G. Giancotti, V. Chau, K.Y. Cranerobinson, C. Expression and cDNA Cloning of Human HMGI-C Phosphoprotein 0006-291X 0006291X Elsevier |
| shingle_title_1 | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein |
| shingle_title_2 | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein |
| shingle_title_3 | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein |
| shingle_title_4 | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:45:45.422Z |
| titel | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein |
| titel_suche | Expression and cDNA Cloning of Human HMGI-C Phosphoprotein The HMGI family contains three members: I, Y and I-C. HMGI and HMGY are alternative splicings of the same gene and are essential transcription factors at several genetic loci. HMGI-C is transcribed from a different gene and is observed only in highly transformed cells. This work shows that human I-C is present in a more restricted range of cell types than I/Y and is absent from hemopoietic cells, as noted for mouse I-C. However, high expression in a human hepatoma line allowed the cloning of the cDNA and 812 bp of 5'-untranslated, 330 bp of coding and 58 bp of 3'-untranslated DNA were sequenced. The open reading frame showed 4 amino acid substitutions and one additional amino acid when compared to mouse I-C, none of them in the basic DNA binding motifs. |
| topic | W V U |
| uid | nat_lic_papers_NLZ183479327 |