Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages
Kawaguchi-Nagata, K. ; Watanabe, T. ; Maeyama, K. ; Yamatodani, A. ; Okamura, H. ; Tamura, T. ; Shoji, K. ; Kitamura, Y.
Amsterdam : Elsevier
Amsterdam : Elsevier
| ISSN: |
0005-2728
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|---|---|
| Keywords: |
(Murine) ; Differentiation ; Histamine ; Histidine decarboxylase ; Macrophages ; Myelomonocytic leukemia cell ; [abr] HDC ; [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) ; [abr] post-endotoxin serum, the serum which was obtained from mice
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| Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
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| Topics: |
Biology
Chemistry and Pharmacology
Medicine
Physics
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798292362826350592 |
|---|---|
| autor | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| autorsonst | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| book_url | http://dx.doi.org/10.1016/S0005-2728(88)80055-0 |
| datenlieferant | nat_lic_papers |
| fussnote | When cells of mouse myelomonocytic leukemia cell line, WEHI-3B, were cultured in the presence of actinomycin D plus the serum which was obtained from mice injected with bacterial endotoxin, i.e., lipopolysaccharide, their histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) (HDC) activity increased about 100-fold with a peak at 48 h. According to the increase in HDC activity, the expression of surface antigens associated with macrophages, such as Mac II, Mac III and Ia^d, increased markedly on WEHI-3B cells as well as their morphological changes to macrophages. Histamine levels in the culture medium increased concomitantly with the increase in the HDC activity in WEHI-3B cells, whereas the histamine contents inside the cells did not increase remarkably. Furthermore, the addition of lipopolysaccharide to the culture medium caused an additional 2-fold increase in the HDC activity of WEHI-3B cells. These results indicate that the increase in HDC activity in WEHI-3B cells may represent an event in the process of the differentiation to macrophages. |
| hauptsatz | hsatz_simple |
| identnr | NLZ177300000 |
| issn | 0005-2728 |
| journal_name | Biochimica et Biophysica Acta (BBA)/Bioenergetics |
| materialart | 1 |
| package_name | Elsevier |
| publikationsort | Amsterdam |
| publisher | Elsevier |
| reference | 972 (1988), S. 249-256 |
| schlagwort | (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice |
| search_space | articles |
| shingle_author_1 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| shingle_author_2 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| shingle_author_3 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| shingle_author_4 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. |
| shingle_catch_all_1 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice 0005-2728 00052728 Elsevier |
| shingle_catch_all_2 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice 0005-2728 00052728 Elsevier |
| shingle_catch_all_3 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice 0005-2728 00052728 Elsevier |
| shingle_catch_all_4 | Kawaguchi-Nagata, K. Watanabe, T. Maeyama, K. Yamatodani, A. Okamura, H. Tamura, T. Shoji, K. Kitamura, Y. Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice (Murine) Differentiation Histamine Histidine decarboxylase Macrophages Myelomonocytic leukemia cell [abr] HDC [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) [abr] post-endotoxin serum, the serum which was obtained from mice 0005-2728 00052728 Elsevier |
| shingle_title_1 | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages |
| shingle_title_2 | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages |
| shingle_title_3 | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages |
| shingle_title_4 | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
| timestamp | 2024-05-06T08:47:19.025Z |
| titel | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages |
| titel_suche | Increase of histidine decarboxylase activity in murine myelomonocytic leukemia cells (WEHI-3B) in parallel to their differentiation into macrophages When cells of mouse myelomonocytic leukemia cell line, WEHI-3B, were cultured in the presence of actinomycin D plus the serum which was obtained from mice injected with bacterial endotoxin, i.e., lipopolysaccharide, their histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) (HDC) activity increased about 100-fold with a peak at 48 h. According to the increase in HDC activity, the expression of surface antigens associated with macrophages, such as Mac II, Mac III and Ia^d, increased markedly on WEHI-3B cells as well as their morphological changes to macrophages. Histamine levels in the culture medium increased concomitantly with the increase in the HDC activity in WEHI-3B cells, whereas the histamine contents inside the cells did not increase remarkably. Furthermore, the addition of lipopolysaccharide to the culture medium caused an additional 2-fold increase in the HDC activity of WEHI-3B cells. These results indicate that the increase in HDC activity in WEHI-3B cells may represent an event in the process of the differentiation to macrophages. |
| topic | W V WW-YZ U |
| uid | nat_lic_papers_NLZ177300000 |