Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression
Cohen, H. ; Gidoni, B. ; Shouval, D. ; Benvenisty, N. ; Mencher, D. ; Meyuhas, O. ; Reshef, L.
Amsterdam : Elsevier
Amsterdam : Elsevier
ISSN: |
0014-5793
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Keywords: |
Gene expression ; Phosphoenolpyruvate carboxykinase
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Source: |
Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
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Topics: |
Biology
Chemistry and Pharmacology
Physics
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Type of Medium: |
Electronic Resource
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URL: |
_version_ | 1798290832354181120 |
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autor | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
autorsonst | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
book_url | http://linkinghub.elsevier.com/retrieve/pii/0014-5793(85)81066-8 |
datenlieferant | nat_lic_papers |
fussnote | Structural conservation of cytosolic phosphoenolpyruvate carboxykinase protein and mRNA sequence was found in all species examined from rodents to human. The mitochondrial isoenzyme, in all species tested, represents a distinct protein. Moreover, irrespective of the ratio of cytosolic to mitochondrial isoenzyme, cytosolic phosphoenolpyruvate carboxykinase activity in the human as in the rat is controlled at the level of gene expression and through the same multiple hormonal stimulation. This evolutionary conservation of the cytosolic phosphoenolpyruvate carboxykinase structure and mode of regulation supports the enzymes' physiological importance in mammals. |
hauptsatz | hsatz_simple |
identnr | NLZ173328288 |
issn | 0014-5793 |
journal_name | FEBS Letters |
materialart | 1 |
package_name | Elsevier |
publikationsort | Amsterdam |
publisher | Elsevier |
reference | 180 (1985), S. 175-180 |
schlagwort | Gene expression Phosphoenolpyruvate carboxykinase |
search_space | articles |
shingle_author_1 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
shingle_author_2 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
shingle_author_3 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
shingle_author_4 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. |
shingle_catch_all_1 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression Gene expression Phosphoenolpyruvate carboxykinase Gene expression Phosphoenolpyruvate carboxykinase 0014-5793 00145793 Elsevier |
shingle_catch_all_2 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression Gene expression Phosphoenolpyruvate carboxykinase Gene expression Phosphoenolpyruvate carboxykinase 0014-5793 00145793 Elsevier |
shingle_catch_all_3 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression Gene expression Phosphoenolpyruvate carboxykinase Gene expression Phosphoenolpyruvate carboxykinase 0014-5793 00145793 Elsevier |
shingle_catch_all_4 | Cohen, H. Gidoni, B. Shouval, D. Benvenisty, N. Mencher, D. Meyuhas, O. Reshef, L. Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression Gene expression Phosphoenolpyruvate carboxykinase Gene expression Phosphoenolpyruvate carboxykinase 0014-5793 00145793 Elsevier |
shingle_title_1 | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression |
shingle_title_2 | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression |
shingle_title_3 | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression |
shingle_title_4 | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression |
sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
source_archive | Elsevier Journal Backfiles on ScienceDirect 1907 - 2002 |
timestamp | 2024-05-06T08:22:59.430Z |
titel | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression |
titel_suche | Conservation from rat to human of cytosolic phosphoenolpyruvate carboxykinase and the control of its gene expression Structural conservation of cytosolic phosphoenolpyruvate carboxykinase protein and mRNA sequence was found in all species examined from rodents to human. The mitochondrial isoenzyme, in all species tested, represents a distinct protein. Moreover, irrespective of the ratio of cytosolic to mitochondrial isoenzyme, cytosolic phosphoenolpyruvate carboxykinase activity in the human as in the rat is controlled at the level of gene expression and through the same multiple hormonal stimulation. This evolutionary conservation of the cytosolic phosphoenolpyruvate carboxykinase structure and mode of regulation supports the enzymes' physiological importance in mammals. |
topic | W V U |
uid | nat_lic_papers_NLZ173328288 |