Orientation, recognition, and photoreaction of nucleolipids in model membranes
| ISSN: |
1435-1536
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| Keywords: |
Nucleolipids ; surfaceinteraction ; monolayer ; photo-dimerization ofthymine-amphiphiles
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Chemistry and Pharmacology
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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| Notes: |
Abstract Amphiphiles with nucleobases and nucleosides as headgroups have been synthesized. Their surface behavior was investigated in monolayers at the air/water interface. The double chain nucleolipids form stable monolayers with nearly identical surface pressure-area diagrams, whereas the spreading behavior of the mono chain amphiphiles is dominated by the various nucleobase-headgroups. When measuring the interactions between nucleolipid monolayers and nucleobases (monomeric and polymeric ones), specific base-base effects could be observed: the complementary nucleobases solubilized in the subphase expand the monolayer more than the non-complementary ones. Photodimerization reactions of thymine-amphiphiles were investigated in mono- and multilayers as well as in spin-coated films.
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| Type of Medium: |
Electronic Resource
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| URL: |