Antagonism by nialamide of the ethanol-induced locomotor stimulation in mice

Ahlenius, S. ; Brown, R. ; Engel, J. ; Svensson, T. H. ; Waldeck, B.
Springer
Published 1974
ISSN:
1435-1463
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Administration of ethanol (2 g/kg, 20% w/v i.p.) to mice produced a significant increase in their locomotor activity. Pretreatment with the monoamine oxidase inhibitor nialamide, whichper se had no marked effect on the locomotor activity, prevented the ethanol-induced locomotor stimulation. The possibility that this effect of nialamide is mediated by a feed-back mechanism is discussed.
Type of Medium:
Electronic Resource
URL: