Polymorphism of the gene of angiotensin converting enzyme: lack of association with mood disorder

Pauls, J. ; Bandelow, B. ; RĂ¼ther, E. ; Kornhuber, J.
Springer
Published 2000
ISSN:
1435-1463
Keywords:
Keywords: Genetic, association, affective disorders, angiotensin converting enzyme, insertion/deletion polymorphism, mood disorders.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary. The insertion/deletion polymorphism of the gene of angiotensin-converting enzyme (ACE) was investigated in a case-control study including 169 patients with suffering from either bipolar disorder type I or unipolar recurrent major depression (DSM-IV) and 169 healthy controls. No significant association was found with bipolar disorder type I or unipolar recurrent depression and the polymorphism of the ACE gene. A previously reported genetic association (Arinami et al., 1996) was not confirmed by the present study.
Type of Medium:
Electronic Resource
URL: