Subcutaneous lymphoblastic lymphomas. Expression of cellular adhesion molecules: 2 cases
Horschowski, N. ; Camoin-Jau, L. ; Bardin, N. ; Brunet, C. ; Arnoux, I. ; Guitard, A. M. ; Fossat, C. ; Hassoun, E. ; Coze, C. ; Gentet, J. C. ; Bernard, J. L. ; Thuret, I. ; Michel, G. ; Dignat-George, F.
Springer
Published 2000
Springer
Published 2000
| ISSN: |
1279-8509
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| Keywords: |
Lymphoblasts ; Lymphoblastic ; Leukemias and lymphomas ; Adhesion molecules
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract We report two cases of subcutaneous lymphomas with a study of cellular adhesion molecules compared to those expressed on blasts at a later blastic phase. The striking different profile of adhesive phenotype in the two conditions is the expression of the interactions of blasts with their microenvironments. It seems that β1 integrins-dependant pathway sustains mainly the development of hematopoietic precursors in extra-medullary niches, while their contact with bone-marrow stroma and their trans-endothelial migration implicates Selectins and Immunoglobulins molecules.
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| Type of Medium: |
Electronic Resource
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| URL: |