DynamicT 1 studies of gadolinium uptake in brain tumors using LL-EPI
Freeman, A. ; Gowland, P. ; Jellineck, D. ; Wilcock, D. ; Firth, J. ; Worthington, B. ; Mansfield, P. ; Ratcliffe, G.
Springer
Published 1994
Springer
Published 1994
| ISSN: |
1352-8661
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|---|---|
| Keywords: |
fastT 1 mapping ; LL-EPI ; dynamic Gd uptake
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
Physics
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| Notes: |
Abstract Using ultrafastT 1 mapping (LL-EPI), the uptake from a bolus injection of Gd-DO3A (ProHance) into the sagittal sinus and a brain tumor has been monitored. The measurement of absoluteT 1 removes the possible error in uptake curves created fromT 1-weighted sequences caused by changes inT 2 * and simplifies the calculation of ProHance concentration. The LL-EPI sequence has an acquisition time of 1.2 s and is repeated every 4 s to obtain uptake curves with a high temporal and spatial resolution. Optimization of the LL-EPI sequence has been performed to obtain a precision of 5% over theT 1 range 0.3–1.2 s.
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| Type of Medium: |
Electronic Resource
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| URL: |