Longitudinal study ofAspergillus fumigatus strains isolated from cystic fibrosis patients
Neuvéglise, C. ; Sarfati, J. ; Debeaupuis, J. P. ; Thien, H. Vu ; Just, J. ; Tournier, G. ; Latgé, J. P.
Springer
Published 1997
Springer
Published 1997
| ISSN: |
1435-4373
|
|---|---|
| Source: |
Springer Online Journal Archives 1860-2000
|
| Topics: |
Medicine
|
| Notes: |
Abstract The colonization over time of cystic fibrosis patients byAspergillus fumigatus was investigated using a DNA fingerprinting method.Aspergillus fumigatus isolates collected sequentially for more than one year from six patients with cystic fibrosis were typed by Southern blot hybridization with a repetitive DNA sequence. Each cystic fibrosis patient harbored several strains ofAspergillus fumigatus that were isolated recurrently over time. Isolates collected from a cystic fibrosis patient with aspergilloma displayed the same genotype, suggesting that the infection was due to a single strain. Continuous isolation of the same genotype in another cystic fibrosis patient, however, was not correlated clinically with anAspergillus infection.
|
| Type of Medium: |
Electronic Resource
|
| URL: |