Trophoblast glycoprotein recognised by monoclonal antibody 5T4 maps to human chromosome 6q14–q15
Boyle, J. M. ; Grzeschik, K. H. ; Heath, P. R. ; Morten, J. E. ; Stern, P. L.
Springer
Published 1990
Springer
Published 1990
| ISSN: |
1432-1203
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary Human × rodent hybrids were stained by indirect immunofluorescence with 5T4, a murine monoclonal antibody that recognises a 72 kdalton glycoprotein expressed by human trophoblasts and a very restricted range of adult tissues; they were analysed by flow cytometry. Concordance analysis supported by segregation data allowed assignment of the gene controlling glycoprotein expression (M6P1) to chromosome 6. Similar analysis with translocation hybrids gave a regional assignment to 6q14–q15. M6P1 is distinct from NT5, coding for 5′ nucleotidase, which maps to the same region.
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| Type of Medium: |
Electronic Resource
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| URL: |