Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1

ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Medicine
Notes:
Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
Type of Medium:
Electronic Resource
URL:
_version_ 1798295621927436288
autor Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
autorsonst Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
book_url http://dx.doi.org/10.1007/BF00278181
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM205618944
issn 1432-1203
journal_name Human genetics 〈Berlin〉
materialart 1
notes Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
package_name Springer
publikationsjahr_anzeige 1988
publikationsjahr_facette 1988
publikationsjahr_intervall 8014:1985-1989
publikationsjahr_sort 1988
publisher Springer
reference 78 (1988), S. 130-133
search_space articles
shingle_author_1 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
shingle_author_2 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
shingle_author_3 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
shingle_author_4 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
shingle_catch_all_1 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
1432-1203
14321203
Springer
shingle_catch_all_2 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
1432-1203
14321203
Springer
shingle_catch_all_3 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
1432-1203
14321203
Springer
shingle_catch_all_4 Rousseau-Merck, M. F.
Simon-Chazottes, D.
Arpin, M.
Pringault, E.
Louvard, D.
Guénet, J. L.
Berger, R.
Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
Summary A partial cDNA clone coding for the 110 carboxyterminal amino acids of human villin was used for mapping the human villin gene. In situ hybridization experiments on human chromosomes with tritiated probe allowed the regional localization of the villin locus to chromosome 2 at q35-36. Data obtained from restriction fragment length polymorphism analysis of two mouse species demonstrated the assignment of the villin gene to mouse chromosome 1 by assessment of linkage with the fast skeletal isoform of the myosin light-chain gene. These villin gene localizations add a fourth locus to the conserved gene cluster encoding the fast skeletal muscle isoform of the myosin light chain, isocitrate dehydrogenase, and the γ crystallins and confirm the partial homology of the human chromosome 2 long arm and mouse chromosome 1.
1432-1203
14321203
Springer
shingle_title_1 Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
shingle_title_2 Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
shingle_title_3 Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
shingle_title_4 Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
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source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:39:07.058Z
titel Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
titel_suche Localization of the villin gene on human chromosome 2q35-q36 and on mouse chromosome 1
topic W
WW-YZ
uid nat_lic_papers_NLM205618944