The presence of androgen-binding receptors in genital and nongenital skin fibroblasts
| ISSN: |
1432-1203
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary The specific, receptor-dependent 5α-dihydrotestosterone-binding capacity of cultured fibroblasts derived from genital and nongenital skin has been compared. With the methods employed, the detectable amount of the DHT receptor in nongenital skin-derived fibroblasts is variable, often approaching the limit of detectability. Therefore it is concluded that for differential diagnosis of disorders of sexual development, DHT-binding studies should be performed with genital skin fibroblasts only.
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| Type of Medium: |
Electronic Resource
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| URL: |