Human alcohol dehydrogenase ADH2 and ADH3 polymorphisms in ethnic Chinese and Indians of West Malaysia

Teng, Y. -S. ; Jehan, S. ; Lie-Injo, L. E.
Springer
Published 1979
ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Medicine
Notes:
Summary Human alcohol dehydrogenase ADH2 and ADH3 were investigated in liver and stomach specimens of Chinese and Indians from West Malaysia. Eight-nine percent of the Chinese carry the atypical ADH2 type, a proportion very similar to that reported in Japanese. However, among 43 Indian specimens there was not a single case of atypical ADH2. In Indians, the gene frequency of ADH3 1 is 0.64 and of ADH3 2 0.36, similar to the frequencies in Caucasians, whereas in Chinese, the gene frequency for ADH3 1 and ADH3 2 is 0.91 and 0.09, respectively. We also report some unusual enzymatic characteristics in the course of our study.
Type of Medium:
Electronic Resource
URL: