“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis

ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Medicine
Notes:
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
Type of Medium:
Electronic Resource
URL:
_version_ 1798295618645393408
autor Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
autorsonst Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
book_url http://dx.doi.org/10.1007/BF00295297
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM205585647
issn 1432-1203
journal_name Human genetics 〈Berlin〉
materialart 1
notes Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
package_name Springer
publikationsjahr_anzeige 1976
publikationsjahr_facette 1976
publikationsjahr_intervall 8024:1975-1979
publikationsjahr_sort 1976
publisher Springer
reference 34 (1976), S. 315-318
search_space articles
shingle_author_1 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
shingle_author_2 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
shingle_author_3 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
shingle_author_4 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
shingle_catch_all_1 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
1432-1203
14321203
Springer
shingle_catch_all_2 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
1432-1203
14321203
Springer
shingle_catch_all_3 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
1432-1203
14321203
Springer
shingle_catch_all_4 Gimelli, G.
Porro, E.
Santi, F.
Scappaticci, Susi
Zuffardi, Orsetta
“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
1432-1203
14321203
Springer
shingle_title_1 “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
shingle_title_2 “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
shingle_title_3 “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
shingle_title_4 “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
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source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:39:02.931Z
titel “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
titel_suche “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
topic W
WW-YZ
uid nat_lic_papers_NLM205585647