“Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis
| ISSN: |
1432-1203
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|---|---|
| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798295618645393408 |
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| autor | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| autorsonst | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| book_url | http://dx.doi.org/10.1007/BF00295297 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM205585647 |
| issn | 1432-1203 |
| journal_name | Human genetics 〈Berlin〉 |
| materialart | 1 |
| notes | Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis. |
| package_name | Springer |
| publikationsjahr_anzeige | 1976 |
| publikationsjahr_facette | 1976 |
| publikationsjahr_intervall | 8024:1975-1979 |
| publikationsjahr_sort | 1976 |
| publisher | Springer |
| reference | 34 (1976), S. 315-318 |
| search_space | articles |
| shingle_author_1 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| shingle_author_2 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| shingle_author_3 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| shingle_author_4 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta |
| shingle_catch_all_1 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis. 1432-1203 14321203 Springer |
| shingle_catch_all_2 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis. 1432-1203 14321203 Springer |
| shingle_catch_all_3 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis. 1432-1203 14321203 Springer |
| shingle_catch_all_4 | Gimelli, G. Porro, E. Santi, F. Scappaticci, Susi Zuffardi, Orsetta “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis Summary Prominent intensely fluorescent satellites on one chromosome 22 seem to have been transferred, during gametogenesis of a male carrier of a balanced 10/22 translocation, from the normal 22 to the translocated 22 in his daughter and son, both carriers of the translocation. Prenatal diagnosis was performed in the carrier daughter and in the chromosomally normal female foetus the satellites have jumped back to one normal chromosome 22. The phenomenon is probably due to exchanges between the short arms of chromosome 22 at meiotic pairing in the father and in his daughter. These observations give a warning for caution in the use of marker variants for paternity tests and prenatal diagnosis. 1432-1203 14321203 Springer |
| shingle_title_1 | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| shingle_title_2 | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| shingle_title_3 | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| shingle_title_4 | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:39:02.931Z |
| titel | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| titel_suche | “Jumping” satellites in three generations: A warning for paternity tests and prenatal diagnosis |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLM205585647 |