Excision of bases accompanying the excision of dimers from DNA of UV-irradiated yeast
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1617-4623
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
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| Notes: |
Summary It is demonstrated that pyrimidine dimers induced in the DNA of yeast by UV irradiation become soluble in weak acid during a period of incubation in growth medium in the dark. This excision is accompanied by the gain of about 18 bases per excised dimer in the acid soluble fraction. The number of dimers as a fraction of total thymine is considerably enhanced in the acid soluble compared to the acid precipitable fraction of cells, suggesting that base excision is specific to dimer-containing regions.
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| Type of Medium: |
Electronic Resource
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| URL: |