Fatal infectious mononucleosis with staphylococcal pyoderma in a girl with hereditary immunological dysregulations
Inaba, T. ; Hanada, R. ; Yaginuma, A. ; Hayashi, Y. ; Yamamoto, K. ; Hukada, H.
Springer
Published 1989
Springer
Published 1989
| ISSN: |
1432-1076
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|---|---|
| Keywords: |
Fatal infectious mononucleosis ; Staphylococcal pyoderma ; Immunodysregulation
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract We describe a 14-year-old girl with fatal infectious mononucleosis with high fever, pancytopenia, and multiple skin ulcers due toStaphylococcus aureus. Immunological studies revealed low serum IgM, low natural killer (NK) activity, and high CD4/CD8 ratio. Her father had also low NK activity and high CD4/CD8 ratio. It is suggested that she had a dominantly inherited immunodeficiency predisposing to severe Epstein-Barr virus infection.
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| Type of Medium: |
Electronic Resource
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| URL: |