Sequence variation of a variable short tandem repeat at the D18S535 locus
| ISSN: |
1437-1596
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| Keywords: |
Key words Short tandem repeats ; Human genome ; DNA sequencing ; DNA polymorphisms
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
Law
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| Notes: |
Abstract A short tandem repeat in the D18S535 locus was sequenced in 25 selected alleles. A total of 8 different alleles were found which can be designated according to the total number of repeats. This STR is a simple hypervariable STR consisting of blocks of (GATA) repeats with a basic sequence structure (GATA)1(GACA)1(GATA)1 (GAT)1(GATA)9–16. Population data showed that this is a highly polymorphic STR with a heterozygosity of more than 0.80, a simple structure and small size (130–158 bp) which makes this an interesting DNA polymorphism for forensic and genetic purposes.
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| Type of Medium: |
Electronic Resource
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| URL: |