Demonstration of amyloid β-protein in a 32-year-old man with progressive dementia

ISSN:
1432-0533
Keywords:
Amyloid β-protein ; Progressive dementia ; Cerebellar plaques
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We report the immunolocalization of extensive amyloid β-protein in senile plaques, cerebrovascular amyloid deposits, neurofibrillary tangles and preamyloid in a 32-year-old man with progressive dementia not to trisomy 21 or trauma. These amyloid deposits were non-reactive to antibodies directed against scrapie amyloid. Our data indicate that the presence of amyloid β-protein is not limited to normal aging, Alzheimer's disease and related disorders but is also found in younger individuals with progressive dementia.
Type of Medium:
Electronic Resource
URL: