Demonstration of amyloid β-protein in a 32-year-old man with progressive dementia
Guiroy, D. C. ; Liberski, P. P. ; Alwasiak, J. ; Papierz, W. ; Gajdusek, D. C.
Springer
Published 1991
Springer
Published 1991
ISSN: |
1432-0533
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Keywords: |
Amyloid β-protein ; Progressive dementia ; Cerebellar plaques
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Source: |
Springer Online Journal Archives 1860-2000
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Topics: |
Medicine
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Notes: |
Summary We report the immunolocalization of extensive amyloid β-protein in senile plaques, cerebrovascular amyloid deposits, neurofibrillary tangles and preamyloid in a 32-year-old man with progressive dementia not to trisomy 21 or trauma. These amyloid deposits were non-reactive to antibodies directed against scrapie amyloid. Our data indicate that the presence of amyloid β-protein is not limited to normal aging, Alzheimer's disease and related disorders but is also found in younger individuals with progressive dementia.
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Type of Medium: |
Electronic Resource
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URL: |