Computer analysis of the entire budding yeast genome for putative targets of the GCN4 transcription factor
| ISSN: |
1432-0983
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| Keywords: |
Key words GCN4 ; Genome ; S. cerevisiae ; Transcription factor
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
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| Notes: |
Abstract The completion of the yeast genome project enables an analysis of various phenomena for a whole eukaryotic genome. We aimed at characterizing a full spectrum of target genes for a transcription activator, and specifically characterized putative targets for GCN4 in the budding yeast. The results suggest that about 1% of the genes are regulated by GCN4 and that these genes code for proteins involved in amino-acid and nucleotide metabolism. Our analysis proposes that, when enough data about the binding nature of a transcription factor exists, it is possible to identify its putative targets and also to try and assign a physiological role for this transcription factor.
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| Type of Medium: |
Electronic Resource
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| URL: |