Renal handling of iodamide and diatrizoate. Evidence of active tubular secretion of iodamide
| ISSN: |
1432-1041
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| Keywords: |
Contrast media ; diatrizoate ; glomerular filtration rate ; iodamide ; tubular secretion
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Chemistry and Pharmacology
Medicine
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| Notes: |
Summary Active tubular secretion of iodamide, a water-soluble contrast medium, was demonstrated by comparing the clearances of iodamide, iothalamate and inulin. Passive tubular back diffusion was not found. The fraction excreted by tubular secretion was significantly reduced at “clinical” plasma concentrations. The glomerular filtration rate was slightly depressed at these concentrations of iodamide and diatrizoate.
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| Type of Medium: |
Electronic Resource
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| URL: |