The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition
Flapan, A. D. ; Davies, E. ; Waugh, C. ; Williams, B. C. ; Shaw, T. R. D. ; Edwards, C. R. W.
Springer
Published 1992
Springer
Published 1992
| ISSN: |
1432-1041
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|---|---|
| Keywords: |
ACE inhibitors ; Posture ; diuretics ; cardiac failure
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Chemistry and Pharmacology
Medicine
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| Notes: |
Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs.
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798295569807966208 |
|---|---|
| autor | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| autorsonst | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| book_url | http://dx.doi.org/10.1007/BF00265919 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM202465438 |
| issn | 1432-1041 |
| journal_name | European journal of clinical pharmacology |
| materialart | 1 |
| notes | Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs. |
| package_name | Springer |
| publikationsjahr_anzeige | 1992 |
| publikationsjahr_facette | 1992 |
| publikationsjahr_intervall | 8009:1990-1994 |
| publikationsjahr_sort | 1992 |
| publisher | Springer |
| reference | 42 (1992), S. 581-585 |
| schlagwort | ACE inhibitors Posture diuretics cardiac failure |
| search_space | articles |
| shingle_author_1 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| shingle_author_2 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| shingle_author_3 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| shingle_author_4 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. |
| shingle_catch_all_1 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition ACE inhibitors Posture diuretics cardiac failure ACE inhibitors Posture diuretics cardiac failure Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs. 1432-1041 14321041 Springer |
| shingle_catch_all_2 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition ACE inhibitors Posture diuretics cardiac failure ACE inhibitors Posture diuretics cardiac failure Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs. 1432-1041 14321041 Springer |
| shingle_catch_all_3 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition ACE inhibitors Posture diuretics cardiac failure ACE inhibitors Posture diuretics cardiac failure Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs. 1432-1041 14321041 Springer |
| shingle_catch_all_4 | Flapan, A. D. Davies, E. Waugh, C. Williams, B. C. Shaw, T. R. D. Edwards, C. R. W. The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition ACE inhibitors Posture diuretics cardiac failure ACE inhibitors Posture diuretics cardiac failure Summary The diuretic and natriuretic response to an intravenous dose of frusemide 40 mg was assessed in the erect and supine positions in 10 patients with cardiac failure who were being treated with enalapril 10 mg twice daily in addition to diuretics (Enalapril group) and in 10 patients with cardiac failure taking diuretics alone (Control group). Total 4 h diuresis in the erect position was 728 ml and in the supine position was 824 ml in the patients taking enalapril compared to 655 ml in the erect position and 1166 ml in the supine position in those patients taking diuretics alone. Total 4 h natriuresis in the erect positions was 78 mmol and in the supine position was 85 mmol in patients taking enalapril 10 mg twice daily but in those patients taking diuretics alone total 4 h natriuresis in the erect position was 67 mmol increasing to 120 mmol in the supine position. Measurements of plasma renin activity and plasma angiotensin II concentration confirmed effective converting enzyme inhibition, in the group of patients taking enalapril, but in those patients taking diuretics alone the erect position was associated with an increase in plasma renin activity, and plasma concentrations of angiotensin II and aldsterone. We conclude that the renin angiotensin system is a major factor in mediating the effect of posture on loop diuretic drugs. 1432-1041 14321041 Springer |
| shingle_title_1 | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| shingle_title_2 | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| shingle_title_3 | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| shingle_title_4 | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:38:18.049Z |
| titel | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| titel_suche | The influence of posture on the response to loop diuretics in patients with chronic cardiac failure is reduced by angiotensin converting enzyme inhibition |
| topic | V WW-YZ |
| uid | nat_lic_papers_NLM202465438 |