Comparative force-frequency relationships in human and other mammalian ventricular myocardium
| ISSN: |
1432-2013
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| Keywords: |
Contraction Velocity ; Force-Frequency Relationship ; Human Myocardium ; Relaxation Velocity
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798295894992355329 |
|---|---|
| autor | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| autorsonst | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| book_url | http://dx.doi.org/10.1007/BF00588574 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM200944703 |
| issn | 1432-2013 |
| journal_name | Pflügers Archiv |
| materialart | 1 |
| notes | Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration. |
| package_name | Springer |
| publikationsjahr_anzeige | 1972 |
| publikationsjahr_facette | 1972 |
| publikationsjahr_intervall | 8029:1970-1974 |
| publikationsjahr_sort | 1972 |
| publisher | Springer |
| reference | 332 (1972), S. 259-270 |
| schlagwort | Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity |
| search_space | articles |
| shingle_author_1 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| shingle_author_2 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| shingle_author_3 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| shingle_author_4 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. |
| shingle_catch_all_1 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. Comparative force-frequency relationships in human and other mammalian ventricular myocardium Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration. 1432-2013 14322013 Springer |
| shingle_catch_all_2 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. Comparative force-frequency relationships in human and other mammalian ventricular myocardium Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration. 1432-2013 14322013 Springer |
| shingle_catch_all_3 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. Comparative force-frequency relationships in human and other mammalian ventricular myocardium Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration. 1432-2013 14322013 Springer |
| shingle_catch_all_4 | Buckley, N. M. Penefsky, Z. J. Litwak, R. S. Comparative force-frequency relationships in human and other mammalian ventricular myocardium Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Contraction Velocity Force-Frequency Relationship Human Myocardium Relaxation Velocity Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration. 1432-2013 14322013 Springer |
| shingle_title_1 | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| shingle_title_2 | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| shingle_title_3 | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| shingle_title_4 | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:43:28.087Z |
| titel | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| titel_suche | Comparative force-frequency relationships in human and other mammalian ventricular myocardium |
| topic | WW-YZ |
| uid | nat_lic_papers_NLM200944703 |