Apolipoprotein E and cholesterol metabolism

Mahley, R. W.
Springer
Published 1983
ISSN:
1432-1440
Keywords:
Apolipoprotein E ; Lipoprotein metabolism
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
Type of Medium:
Electronic Resource
URL:
_version_ 1798295718529597440
autor Mahley, R. W.
autorsonst Mahley, R. W.
book_url http://dx.doi.org/10.1007/BF01496128
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM199367043
issn 1432-1440
journal_name Journal of molecular medicine
materialart 1
notes Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
package_name Springer
publikationsjahr_anzeige 1983
publikationsjahr_facette 1983
publikationsjahr_intervall 8019:1980-1984
publikationsjahr_sort 1983
publisher Springer
reference 61 (1983), S. 225-232
schlagwort Apolipoprotein E
Lipoprotein metabolism
search_space articles
shingle_author_1 Mahley, R. W.
shingle_author_2 Mahley, R. W.
shingle_author_3 Mahley, R. W.
shingle_author_4 Mahley, R. W.
shingle_catch_all_1 Mahley, R. W.
Apolipoprotein E and cholesterol metabolism
Apolipoprotein E
Lipoprotein metabolism
Apolipoprotein E
Lipoprotein metabolism
Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
1432-1440
14321440
Springer
shingle_catch_all_2 Mahley, R. W.
Apolipoprotein E and cholesterol metabolism
Apolipoprotein E
Lipoprotein metabolism
Apolipoprotein E
Lipoprotein metabolism
Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
1432-1440
14321440
Springer
shingle_catch_all_3 Mahley, R. W.
Apolipoprotein E and cholesterol metabolism
Apolipoprotein E
Lipoprotein metabolism
Apolipoprotein E
Lipoprotein metabolism
Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
1432-1440
14321440
Springer
shingle_catch_all_4 Mahley, R. W.
Apolipoprotein E and cholesterol metabolism
Apolipoprotein E
Lipoprotein metabolism
Apolipoprotein E
Lipoprotein metabolism
Summary The role of apo-E in mediating lipoprotein interaction with specific receptors has been established. Through the use of selective chemical modification of specific amino acid residues of certain lipoproteins, we have gained insight into the importance of the lysine and arginine residues in this process. This understanding has been expanded by structure-function studies of mutant forms of apo-E. These studies have revealed important information concerning the genetic heterogeneity of the apo-E isoforms, focusing attention on the importance of a specific region of apo-E in the binding process.
1432-1440
14321440
Springer
shingle_title_1 Apolipoprotein E and cholesterol metabolism
shingle_title_2 Apolipoprotein E and cholesterol metabolism
shingle_title_3 Apolipoprotein E and cholesterol metabolism
shingle_title_4 Apolipoprotein E and cholesterol metabolism
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
fhp
source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:40:39.788Z
titel Apolipoprotein E and cholesterol metabolism
titel_suche Apolipoprotein E and cholesterol metabolism
topic WW-YZ
uid nat_lic_papers_NLM199367043