A Retrospective Follow-Up Study on Intracytoplasmic Sperm Injection
Van Golde, R. ; Boada, M. ; Veiga, A. ; Evers, J. ; Geraedts, J. ; Barri, P.
Springer
Published 1999
Springer
Published 1999
| ISSN: |
1573-7330
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|---|---|
| Keywords: |
ICSI ; retrospective follow-up ; pregnancy ; children
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract Purpose: Genetic aspects of male subfertility and the novelty of intracytoplasmic sperm injection (ICSI) as a new technique can influence the development of zygotes and children born after ICSI. Therefore, we evaluated the outcome of ICSI compared to in vitro fertilization (IVF). Methods: Data from medical records of 233 total pregnancies and the follow-up of 132 children born after IVF and 120 after ICSI were retrospectively analyzed. Results: No differences were found between ICSI and IVF for early embryonic development and obstetric outcome. In both groups the rate of women undergoing prenatal chromosomal diagnosis was low, 30.0%. The congenital malformation rate was 3.0% after IVF and 1.7% after ICSI, which was not significantly different. Follow-up on development of children born after IVF and ICSI also showed no significant differences. Conclusions: Our results indicate that at this moment ICSI is a safe procedure. However, a consistent prospective follow-up is still mandatory to exclude possible risks.
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| Type of Medium: |
Electronic Resource
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| URL: |