Changes in brain choline acetylase and choline esterase during generalized hypothermia
| ISSN: |
1573-8221
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary A study has been made of the choline acetylase and esterase activities of brains of rats under ether anesthesia, in hypothermia, and during emergence from hypothermia. Ether anesthesia was associated with a considerable rise in choline acetylase, and a smaller rise in choline esterase, activity. Generalized hypothermia of ether-anesthetized rats was invariably associated with fall in choline acetylase activity, as well as, in most cases, in choline esterase activity. During recovery from the hypothermic state rises in the activity of both enzymes were noted. The parallelism of the changes in the activities of the two enzymes suggests that they may have an adaptive-compensatory nature. Disturbances in the correlation of the two activities may lead to changes in acetylcholine metabolism.
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| Type of Medium: |
Electronic Resource
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| URL: |