Plasma DNA levels in patients with atherosclerotic involvement of the major arteries of the head and lateral amyotrophic sclerosis
Gannushkina, I. V. ; Farago, M. L. ; Karpukhin, A. V. ; Veiko, N. N. ; Dzhibladze, D. N. ; Zavalishin, I. A.
Springer
Published 1997
Springer
Published 1997
| ISSN: |
1573-8221
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|---|---|
| Keywords: |
DNA ; fluorometry ; bisBenzimide ; cerebral circulation disorders ; lateral amyotrophic sclerosis
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Abstract Measurements of DNA concentrations by fluorescence of the DNA-bisBenzimide complex in the plasma of normal subjects, patients with disorders of cerebral circulation of different severity caused by atherosclerotic involvement of the carotid and/or spinal arteries (after the acute stage of brain stroke), and patients with lateral amyotrophic sclerosis showed a significant increase in its contentvs. the norm. Electrophoresis of DNA isolated from plasma showed that in the patients it is represented not only by long fragments of at least 20,000 bp (which is typical of normal subjects), but also by shorter fragments.
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| Type of Medium: |
Electronic Resource
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| URL: |