Effect of sevoflurane on P50 and on measurement of oxygen tension
Kambam, J. Reddy ; Horton, Bennett F. ; Parris, Winston C. V. ; Holaday, Duncan A.
Springer
Published 1988
Springer
Published 1988
| ISSN: |
1573-2614
|
|---|---|
| Keywords: |
Anesthetics: sevoflurane ; Blood: hemoglobin ; Oxygen: tension ; Monitoring: oxygen
|
| Source: |
Springer Online Journal Archives 1860-2000
|
| Topics: |
Computer Science
Medicine
|
| Notes: |
Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference.
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798296650813276160 |
|---|---|
| autor | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| autorsonst | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| book_url | http://dx.doi.org/10.1007/BF01617323 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM194844250 |
| issn | 1573-2614 |
| journal_name | Journal of clinical monitoring and computing |
| materialart | 1 |
| notes | Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference. |
| package_name | Springer |
| publikationsjahr_anzeige | 1988 |
| publikationsjahr_facette | 1988 |
| publikationsjahr_intervall | 8014:1985-1989 |
| publikationsjahr_sort | 1988 |
| publisher | Springer |
| reference | 4 (1988), S. 261-263 |
| schlagwort | Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen |
| search_space | articles |
| shingle_author_1 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| shingle_author_2 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| shingle_author_3 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| shingle_author_4 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. |
| shingle_catch_all_1 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. Effect of sevoflurane on P50 and on measurement of oxygen tension Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference. 1573-2614 15732614 Springer |
| shingle_catch_all_2 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. Effect of sevoflurane on P50 and on measurement of oxygen tension Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference. 1573-2614 15732614 Springer |
| shingle_catch_all_3 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. Effect of sevoflurane on P50 and on measurement of oxygen tension Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference. 1573-2614 15732614 Springer |
| shingle_catch_all_4 | Kambam, J. Reddy Horton, Bennett F. Parris, Winston C. V. Holaday, Duncan A. Effect of sevoflurane on P50 and on measurement of oxygen tension Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Anesthetics: sevoflurane Blood: hemoglobin Oxygen: tension Monitoring: oxygen Abstract Fresh samples of heparinized human blood from 10 healthy nonsmoking volunteers were used to study the effect of the inhaled anesthetic sevoflurane on the oxygen half-saturation pressure of hemoglobin (P50) and on polarographic measurements of oxygen tension at low values. Control samples had a baseline P50 of 26.9±0.2 mm Hg. When the blood samples were exposed to 1.75% (1 minimum alveolar concentration, MAC), 2.75%, and 3.5% (2 MAC) of sevoflurane, the P50 values were 27.0±0.5 mm Hg, 27.1±0.4 mm Hg, and 26.9±0.5 mm Hg, respectively. Our present data show that 1 to 2 MAC sevoflurane has no significant effect on P50 (P〉0.05). Our data also show that sevoflurane did not interfere with polarographic measurements of oxygen tension (P〉0.05). Other inhaled agents—halothane, enflurane, and isoflurane—do interfere with these measurements, and we cannot explain the difference. 1573-2614 15732614 Springer |
| shingle_title_1 | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| shingle_title_2 | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| shingle_title_3 | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| shingle_title_4 | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:55:27.961Z |
| titel | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| titel_suche | Effect of sevoflurane on P50 and on measurement of oxygen tension |
| topic | SQ-SU WW-YZ |
| uid | nat_lic_papers_NLM194844250 |