Central function and visual field damage in glaucoma

Lachenmayr, Bernhard J. ; Drance, Stephen M.
Springer
Published 1992
ISSN:
1573-2630
Keywords:
glaucoma ; central function ; visual field damage ; mechanisms of glaucomatous damage
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
Type of Medium:
Electronic Resource
URL:
_version_ 1798296653870923777
autor Lachenmayr, Bernhard J.
Drance, Stephen M.
autorsonst Lachenmayr, Bernhard J.
Drance, Stephen M.
book_url http://dx.doi.org/10.1007/BF00917962
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM194444600
issn 1573-2630
journal_name International ophthalmology
materialart 1
notes Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
package_name Springer
publikationsjahr_anzeige 1992
publikationsjahr_facette 1992
publikationsjahr_intervall 8009:1990-1994
publikationsjahr_sort 1992
publisher Springer
reference 16 (1992), S. 203-209
schlagwort glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
search_space articles
shingle_author_1 Lachenmayr, Bernhard J.
Drance, Stephen M.
shingle_author_2 Lachenmayr, Bernhard J.
Drance, Stephen M.
shingle_author_3 Lachenmayr, Bernhard J.
Drance, Stephen M.
shingle_author_4 Lachenmayr, Bernhard J.
Drance, Stephen M.
shingle_catch_all_1 Lachenmayr, Bernhard J.
Drance, Stephen M.
Central function and visual field damage in glaucoma
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
1573-2630
15732630
Springer
shingle_catch_all_2 Lachenmayr, Bernhard J.
Drance, Stephen M.
Central function and visual field damage in glaucoma
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
1573-2630
15732630
Springer
shingle_catch_all_3 Lachenmayr, Bernhard J.
Drance, Stephen M.
Central function and visual field damage in glaucoma
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
1573-2630
15732630
Springer
shingle_catch_all_4 Lachenmayr, Bernhard J.
Drance, Stephen M.
Central function and visual field damage in glaucoma
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
glaucoma
central function
visual field damage
mechanisms of glaucomatous damage
Abstract 82 eyes of 82 patients with different types of glaucoma were examined with various psychophysical tests assessing central and paracentral function, including foveal temporal contrast sensitivity function, FM 100-Hue test, and foveal and parafoveal blue-on-yellow-sensitivity. For all eyes visual field tests were performed with the Humphrey-Field-Analyzer, program 30-2. Global visual field indices were calculated as follows: Mean Sensitivity MS, Mean Deviation MD, and Corrected Pattern Standard Deviation CPSD. Linear regression analysis and multiple regression analysis correcting for a possible influence of age between the central and paracentral criteria and the global indices was performed. For the entire study population highly significant correlations are present between foveal and parafoveal blue-on-yellow-sensitivity and MS, MD and CPSD. Whereas in the Normal Tension Glaucoma subgroup (19/82 eyes) no significant correlations are found, the subgroup of 35/82 eyes with markedly elevated intraocular pressure (≥30mmHg) shows highly statistically significant correlations between the low- and high-frequency end of the foveal temporal contrast sensitivity function and foveal and parafoveal blue-on-yellow-sensitivity and the global field indices. The results of the present study support the idea that there are two different mechanisms of glaucomatous damage, one which is pressure-dependent and one which may be pressure-independent. The pressuredependent mechanism is responsible for deficits of central or paracentral function which are correlated to overall visual field damage.
1573-2630
15732630
Springer
shingle_title_1 Central function and visual field damage in glaucoma
shingle_title_2 Central function and visual field damage in glaucoma
shingle_title_3 Central function and visual field damage in glaucoma
shingle_title_4 Central function and visual field damage in glaucoma
sigel_instance_filter dkfz
geomar
wilbert
ipn
albert
fhp
source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:55:31.938Z
titel Central function and visual field damage in glaucoma
titel_suche Central function and visual field damage in glaucoma
topic WW-YZ
uid nat_lic_papers_NLM194444600