Effects of timolol on visual-field mean retinal sensitivity in normal subjects
| ISSN: |
1573-2630
|
|---|---|
| Keywords: |
automated perimetry ; maleate timolol ; mean sensitivity ; visual field
|
| Source: |
Springer Online Journal Archives 1860-2000
|
| Topics: |
Medicine
|
| Notes: |
Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy.
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798296653852049408 |
|---|---|
| autor | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| autorsonst | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| book_url | http://dx.doi.org/10.1007/BF00917985 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM194444414 |
| issn | 1573-2630 |
| journal_name | International ophthalmology |
| materialart | 1 |
| notes | Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy. |
| package_name | Springer |
| publikationsjahr_anzeige | 1992 |
| publikationsjahr_facette | 1992 |
| publikationsjahr_intervall | 8009:1990-1994 |
| publikationsjahr_sort | 1992 |
| publisher | Springer |
| reference | 16 (1992), S. 325-329 |
| schlagwort | automated perimetry maleate timolol mean sensitivity visual field |
| search_space | articles |
| shingle_author_1 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| shingle_author_2 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| shingle_author_3 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| shingle_author_4 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. |
| shingle_catch_all_1 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. Effects of timolol on visual-field mean retinal sensitivity in normal subjects automated perimetry maleate timolol mean sensitivity visual field automated perimetry maleate timolol mean sensitivity visual field Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy. 1573-2630 15732630 Springer |
| shingle_catch_all_2 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. Effects of timolol on visual-field mean retinal sensitivity in normal subjects automated perimetry maleate timolol mean sensitivity visual field automated perimetry maleate timolol mean sensitivity visual field Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy. 1573-2630 15732630 Springer |
| shingle_catch_all_3 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. Effects of timolol on visual-field mean retinal sensitivity in normal subjects automated perimetry maleate timolol mean sensitivity visual field automated perimetry maleate timolol mean sensitivity visual field Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy. 1573-2630 15732630 Springer |
| shingle_catch_all_4 | Martin, Xavier D. Fankhauser, Franz Rabineau, Paul A. Effects of timolol on visual-field mean retinal sensitivity in normal subjects automated perimetry maleate timolol mean sensitivity visual field automated perimetry maleate timolol mean sensitivity visual field Abstract This single-blind, randomized study investigated the effects of unilateral instillation of 0.5% maleate timolol twice a day for 7 days on visual-field parameters of both eyes. Twelve normal, young subjects (30.6±4.2 years) participated in this study. Using program Gl of the Octopus 500 automated perimeter, the visual fields were measured one week and one day before therapy and a third time one week after beginning therapy. The paired T-test was used for statistical analysis, where a P-value⩽0.05 indicated significance. Whereas nothing statistically significant was found in the treated eyes, the contralateral, untreated eyes showed a statistically significant decrease of mean sensitivity between the first visual fields and the third ones (P〈 0.01) This diminution of mean sensitivity in the untreated contralateral eyes may be due to statistically significant lowering of blood pressure (P〈0.01) and slowing of cardiac frequency, which were not compensated by a local decrease of intraocular pressure. If confirmed, these findings could be of clinical importance in the management of glaucoma patients, since some authors have, in some cases, recommended a unilateral therapy. 1573-2630 15732630 Springer |
| shingle_title_1 | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| shingle_title_2 | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| shingle_title_3 | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| shingle_title_4 | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:55:31.938Z |
| titel | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| titel_suche | Effects of timolol on visual-field mean retinal sensitivity in normal subjects |
| topic | WW-YZ |
| uid | nat_lic_papers_NLM194444414 |