Clinical profiles of non dry eye patients and correlations with tear protein levels

Snyder, Christopher ; Fullard, Roderick J.
Springer
Published 1991
ISSN:
1573-2630
Keywords:
clinical tests ; dry eye ; normal clinical profile ; tear proteins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
Type of Medium:
Electronic Resource
URL:
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autor Snyder, Christopher
Fullard, Roderick J.
autorsonst Snyder, Christopher
Fullard, Roderick J.
book_url http://dx.doi.org/10.1007/BF00137949
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM194443752
issn 1573-2630
journal_name International ophthalmology
materialart 1
notes Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
package_name Springer
publikationsjahr_anzeige 1991
publikationsjahr_facette 1991
publikationsjahr_intervall 8009:1990-1994
publikationsjahr_sort 1991
publisher Springer
reference 15 (1991), S. 383-389
schlagwort clinical tests
dry eye
normal clinical profile
tear proteins
search_space articles
shingle_author_1 Snyder, Christopher
Fullard, Roderick J.
shingle_author_2 Snyder, Christopher
Fullard, Roderick J.
shingle_author_3 Snyder, Christopher
Fullard, Roderick J.
shingle_author_4 Snyder, Christopher
Fullard, Roderick J.
shingle_catch_all_1 Snyder, Christopher
Fullard, Roderick J.
Clinical profiles of non dry eye patients and correlations with tear protein levels
clinical tests
dry eye
normal clinical profile
tear proteins
clinical tests
dry eye
normal clinical profile
tear proteins
Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
1573-2630
15732630
Springer
shingle_catch_all_2 Snyder, Christopher
Fullard, Roderick J.
Clinical profiles of non dry eye patients and correlations with tear protein levels
clinical tests
dry eye
normal clinical profile
tear proteins
clinical tests
dry eye
normal clinical profile
tear proteins
Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
1573-2630
15732630
Springer
shingle_catch_all_3 Snyder, Christopher
Fullard, Roderick J.
Clinical profiles of non dry eye patients and correlations with tear protein levels
clinical tests
dry eye
normal clinical profile
tear proteins
clinical tests
dry eye
normal clinical profile
tear proteins
Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
1573-2630
15732630
Springer
shingle_catch_all_4 Snyder, Christopher
Fullard, Roderick J.
Clinical profiles of non dry eye patients and correlations with tear protein levels
clinical tests
dry eye
normal clinical profile
tear proteins
clinical tests
dry eye
normal clinical profile
tear proteins
Abstract An accurate clinical description of the normal patient must be established before the dry eye patient can be accurately profiled. The current study was designed to (a) determine normal values for, and to seek correlations between, clinical tests used for the evaluation of non dry eye patients' tear film and ocular surface, and (b) compare clinical findings with previously reported levels of non-stimulated and stimulated tear proteins for the same group. Thirty non-contact lens wearing patients (age range 20–64 years) were determined to be free of dry eye based on the results of a series of clinical tests. McMonnie's dry eye questionnaire was used as an initial screening step. Clinical tests included lacrimation kinetics (using sealed, calibrated filter paper strips), non-invasive tear break-up time (NIBUT) measurement by Xeroscope, biomicroscopic evaluation of the anterior segment, assessment of tear prism height and regularity, and fluorescein and Rose Bengal staining. No significant correlations were found between age, questionnaire score, lacrimation kinetics final tear secretion rate or NIBUT. However, NIBUT results did vary by gender. Mean NIBUT for females was 46.3 ± 16.6 (standard deviation) seconds and for males 59.3 ± 2.1 seconds. Some significant correlations were found between clinical test results and levels of non-stimulated and stimulated tear proteins. Overall, the results indicate that this battery of clinical tests will be appropriate for distinguishing between normal and dry eye patients. Combined with tear protein assay, this clinical approach may improve our current understanding of the different types of dry eye.
1573-2630
15732630
Springer
shingle_title_1 Clinical profiles of non dry eye patients and correlations with tear protein levels
shingle_title_2 Clinical profiles of non dry eye patients and correlations with tear protein levels
shingle_title_3 Clinical profiles of non dry eye patients and correlations with tear protein levels
shingle_title_4 Clinical profiles of non dry eye patients and correlations with tear protein levels
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titel Clinical profiles of non dry eye patients and correlations with tear protein levels
titel_suche Clinical profiles of non dry eye patients and correlations with tear protein levels
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