Liposome-bound cyclosporine: Clearance after intravitreal injection
Alghadyan, Abdulrahman A. ; Peyman, Gholam A. ; Khoobehi, Bahram ; Milner, Steve ; Liu, Kwan-Rong
Springer
Published 1988
Springer
Published 1988
| ISSN: |
1573-2630
|
|---|---|
| Keywords: |
aqueous ; cyclosporine ; HPLC ; liposome ; rabbit ; vitreous
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| Source: |
Springer Online Journal Archives 1860-2000
|
| Topics: |
Medicine
|
| Notes: |
Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug.
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| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798296654109999104 |
|---|---|
| autor | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| autorsonst | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| book_url | http://dx.doi.org/10.1007/BF00137135 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM194441091 |
| issn | 1573-2630 |
| journal_name | International ophthalmology |
| materialart | 1 |
| notes | Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug. |
| package_name | Springer |
| publikationsjahr_anzeige | 1988 |
| publikationsjahr_facette | 1988 |
| publikationsjahr_intervall | 8014:1985-1989 |
| publikationsjahr_sort | 1988 |
| publisher | Springer |
| reference | 12 (1988), S. 109-112 |
| schlagwort | aqueous cyclosporine HPLC liposome rabbit vitreous |
| search_space | articles |
| shingle_author_1 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| shingle_author_2 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| shingle_author_3 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| shingle_author_4 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong |
| shingle_catch_all_1 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong Liposome-bound cyclosporine: Clearance after intravitreal injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug. 1573-2630 15732630 Springer |
| shingle_catch_all_2 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong Liposome-bound cyclosporine: Clearance after intravitreal injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug. 1573-2630 15732630 Springer |
| shingle_catch_all_3 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong Liposome-bound cyclosporine: Clearance after intravitreal injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug. 1573-2630 15732630 Springer |
| shingle_catch_all_4 | Alghadyan, Abdulrahman A. Peyman, Gholam A. Khoobehi, Bahram Milner, Steve Liu, Kwan-Rong Liposome-bound cyclosporine: Clearance after intravitreal injection aqueous cyclosporine HPLC liposome rabbit vitreous aqueous cyclosporine HPLC liposome rabbit vitreous Abstract The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug. 1573-2630 15732630 Springer |
| shingle_title_1 | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| shingle_title_2 | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| shingle_title_3 | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| shingle_title_4 | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:55:31.733Z |
| titel | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| titel_suche | Liposome-bound cyclosporine: Clearance after intravitreal injection |
| topic | WW-YZ |
| uid | nat_lic_papers_NLM194441091 |