Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus
| ISSN: |
1573-5168
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| Keywords: |
tilapia ; larvae ; toxicity ; development ; cadmium ; calcium ; Ca2+ influx ; Km ; Vmax
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
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| Notes: |
Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798296835884843008 |
|---|---|
| autor | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| autorsonst | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| book_url | http://dx.doi.org/10.1023/A:1007780602426 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM193945304 |
| issn | 1573-5168 |
| journal_name | Fish physiology and biochemistry |
| materialart | 1 |
| notes | Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning. |
| package_name | Springer |
| publikationsjahr_anzeige | 1997 |
| publikationsjahr_facette | 1997 |
| publikationsjahr_intervall | 8004:1995-1999 |
| publikationsjahr_sort | 1997 |
| publisher | Springer |
| reference | 16 (1997), S. 459-470 |
| schlagwort | tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax |
| search_space | articles |
| shingle_author_1 | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| shingle_author_2 | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| shingle_author_3 | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| shingle_author_4 | Chang, M.-H. Lin, H.-C. Hwang, P.P. |
| shingle_catch_all_1 | Chang, M.-H. Lin, H.-C. Hwang, P.P. Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning. 1573-5168 15735168 Springer |
| shingle_catch_all_2 | Chang, M.-H. Lin, H.-C. Hwang, P.P. Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning. 1573-5168 15735168 Springer |
| shingle_catch_all_3 | Chang, M.-H. Lin, H.-C. Hwang, P.P. Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning. 1573-5168 15735168 Springer |
| shingle_catch_all_4 | Chang, M.-H. Lin, H.-C. Hwang, P.P. Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax tilapia larvae toxicity development cadmium calcium Ca2+ influx Km Vmax Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning. 1573-5168 15735168 Springer |
| shingle_title_1 | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| shingle_title_2 | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| shingle_title_3 | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| shingle_title_4 | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| sigel_instance_filter | dkfz geomar wilbert ipn albert fhp |
| source_archive | Springer Online Journal Archives 1860-2000 |
| timestamp | 2024-05-06T09:58:25.565Z |
| titel | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| titel_suche | Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus |
| topic | W |
| uid | nat_lic_papers_NLM193945304 |