Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress

ISSN:
1573-0743
Keywords:
2D-echo ; Tc99m Sestamibi ; CAD ; women
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
Type of Medium:
Electronic Resource
URL:
_version_ 1798296550261129216
autor Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
autorsonst Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
book_url http://dx.doi.org/10.1007/BF01880742
datenlieferant nat_lic_papers
hauptsatz hsatz_simple
identnr NLM193537117
issn 1573-0743
journal_name The international journal of cardiovascular imaging
materialart 1
notes Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
package_name Springer
publikationsjahr_anzeige 1996
publikationsjahr_facette 1996
publikationsjahr_intervall 8004:1995-1999
publikationsjahr_sort 1996
publisher Springer
reference 12 (1996), S. 113-118
schlagwort 2D-echo
Tc99m Sestamibi
CAD
women
search_space articles
shingle_author_1 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
shingle_author_2 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
shingle_author_3 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
shingle_author_4 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
shingle_catch_all_1 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
2D-echo
Tc99m Sestamibi
CAD
women
2D-echo
Tc99m Sestamibi
CAD
women
Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
1573-0743
15730743
Springer
shingle_catch_all_2 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
2D-echo
Tc99m Sestamibi
CAD
women
2D-echo
Tc99m Sestamibi
CAD
women
Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
1573-0743
15730743
Springer
shingle_catch_all_3 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
2D-echo
Tc99m Sestamibi
CAD
women
2D-echo
Tc99m Sestamibi
CAD
women
Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
1573-0743
15730743
Springer
shingle_catch_all_4 Slavich, G. A.
Guerra, U. P.
Morocutti, G.
Fioretti, P. M.
Fresco, C.
Orlandi, C.
Orsolon, P. G.
Forster, T.
Feruglio, G. A.
Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
2D-echo
Tc99m Sestamibi
CAD
women
2D-echo
Tc99m Sestamibi
CAD
women
Abstract Feasibility of simultaneous 2D-Echo and SPECT Tc99m Sestamibi imaging during dobutamine infusion was evaluated in a female population with suspected coronary artery disease and scheduled for diagnostic coronary angiography. A total of 49 consecutive subjects were studied. Patients under continuous ECG and 2D-Echo monitoring underwent standard dobutamine infusion at increasing doses to a diagnostic end-point. Tc99m Sestamibi was administered at the peak of the dobutamine effect. With this approach, 35 patients were identified correctly by 2D-Echo (Sensitivity = 60.1%; Specificity = 83.3%; Agreement = 71.4%; k = 0.43). Perfusion imaging with Tc99m Sestamibi resulted in correctly identifying 41 patients (Sensitivity = 83%; Specificity = 84%; Agreement = 83.6%; k=0.67). Combining information obtained from the two tests resulted in increased specificity (92%) and decreased sensitivity (64%). Simultaneous assessment of perfusion and function with Tc99m Sestamibi and 2D-Echo imaging during dobutamine administration is easily performed without added risk or discomfort to the patient. Tc99m Sestamibi appeared to be slightly superior to 2D-Echo for the detection of CAD in this population, but the difference does not reach conventional statistical significance. The combined use of the two independent tests did not substantially improve the diagnostic accuracy of each method.
1573-0743
15730743
Springer
shingle_title_1 Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
shingle_title_2 Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
shingle_title_3 Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
shingle_title_4 Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
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source_archive Springer Online Journal Archives 1860-2000
timestamp 2024-05-06T09:53:52.987Z
titel Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
titel_suche Feasibility of simultaneous Tc99m sestamibi and 2D-echo cardiac imaging during dobutamine pharmacologic stress
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