Lifetime menstrual activity — Indicator of breast cancer risk
Rautalahti, M. ; Albanes, D. ; Virtamo, J. ; Palmgren, J. ; Haukka, J. ; Heinonen, O. P.
Springer
Published 1993
Springer
Published 1993
| ISSN: |
1573-7284
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|---|---|
| Keywords: |
Breast cancer ; Risk ; Menstrual
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract A case-control study of 67 cases of breast cancer and 157 controls was conducted to investigate the role of different behavioral, reproductive, and hormonal factors and to develop a unifying indicator of breast cancer risk. The results confirm previous reports of the influence of smoking on the risk of breast cancer. Age at menarche was found to be a risk factor among the premenopausa women. Late age at menopause was suggestive of an increase in risk. Long use of oral contraceptive or estrogen supplementation were risk-enhancing both pre- and postmenopausally. Lifetime duration of menstrual activity (LMA) combines age at menarche and menopause, parity, and lactation into a biologically plausible model. Our findings concerning LMA support its role as a determinant of breast cancer.
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| Type of Medium: |
Electronic Resource
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| URL: |