Use of macroreticular resins for the adsorption of urokinase from human urine

ISSN:
1573-6776
Source:
Springer Online Journal Archives 1860-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary 22 commercial macroreticular resins were screened for their suitability to adsorb the enzyme urokinase directly from human urine at the outlet of a urinal. Both batch and fixed bed techniques were used for the screening, which identified a phenolic resin (Duolite S-762) as having the best capacity and adsorption efficiency. A capacity in excess of 1800 IU/ml. resin is attainable, and elution with 50% ethanolamine followed by immediate neutralisation with HCl gives satisfactory recovery of activity.
Type of Medium:
Electronic Resource
URL: