Selectivity of alterations in skeletal fibers in chronic Chagas' disease of the mouse

Meckert, P. M. Cabeza ; Laguens, R. P.
Springer
Published 1988
ISSN:
1420-9071
Keywords:
Trypanosoma cruzi ; Chagas' disease ; skeletal muscle ; tissue tropism
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Medicine
Notes:
Summary In mice chronically infected withTrypanosoma cruzi, the masseter muscle (rich in type II fibers) was devoid of inflammatory infiltrates and parasites. In contrast, other muscles, composed of type I and II fibers, showed a decrease of type I fibers, parasites and lesions, suggesting that inT. cruzi infection type I muscle fibers are selectively damaged.
Type of Medium:
Electronic Resource
URL: