Variations in cardiac noradrenaline content during sodium loading in hypertension prone and resistant rats
Quan-Bui, K. H. ; Devynck, Marie-Aude ; Pernollet, Marie-Gabrielle ; Ben-Ishay, D. ; Meyer, P.
Springer
Published 1981
Springer
Published 1981
| ISSN: |
1420-9071
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|---|---|
| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Biology
Medicine
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| Notes: |
Summary The cardiac catecholamine content of Sabra rats and their 2 genetically derived substrains, hypertension prone and resistant rats, was studied by high pressure liquid chromatography and electrochemical detection. Both in the control period and after sodium and DOCA administration the cardiac noradrenaline level is higher in hypertension resistant rats than in Sabra rats, and also higher than in hypertension prone rats. This finding suggests that a reduction of the cardiac sympathetic nervous tone is involved in the genetic resistance to sodium.
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| Type of Medium: |
Electronic Resource
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| URL: |