Effect of inflammatory arthritis on dexamethasone receptors in phagocytes—a possible role for plasma factors
Braidman, Isobel P. ; Livingston, K. ; Tomlinson, I. W. ; Jayson, M. I. V. ; Jasani, M. K.
Springer
Published 1981
Springer
Published 1981
| ISSN: |
1420-908X
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| Source: |
Springer Online Journal Archives 1860-2000
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| Topics: |
Medicine
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| Notes: |
Abstract Synovial tissue cells from patients with seropositive rheumatoid arthritis bind dexamethasone in a similar fashion to the classical steroid receptors on other cells. In contrast, synovial fluid cells and blood PMNLs from these patients bind dexamethasone with much reduced affinity. Some component of plasma may interfere with the binding of dexamethasone to its receptor.
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| Type of Medium: |
Electronic Resource
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| URL: |