Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada.
Brooks, D. E. ; Millar, J. S. ; Seaman, G. V. F. ; Vassar, P. S.
New York, NY [u.a.] : Wiley-Blackwell
Published 1967
New York, NY [u.a.] : Wiley-Blackwell
Published 1967
| ISSN: |
0021-9541
|
|---|---|
| Keywords: |
Life and Medical Sciences ; Cell & Developmental Biology
|
| Source: |
Wiley InterScience Backfile Collection 1832-2000
|
| Topics: |
Biology
Medicine
|
| Notes: |
Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells.
|
| Additional Material: |
4 Ill.
|
| Type of Medium: |
Electronic Resource
|
| URL: |
| _version_ | 1798297987876651010 |
|---|---|
| addmaterial | 4 Ill. |
| autor | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| autorsonst | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| book_url | http://dx.doi.org/10.1002/jcp.1040690206 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM160756898 |
| issn | 0021-9541 |
| journal_name | Journal of Cellular Physiology |
| materialart | 1 |
| notes | Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells. |
| package_name | Wiley-Blackwell |
| publikationsjahr_anzeige | 1967 |
| publikationsjahr_facette | 1967 |
| publikationsjahr_intervall | 8034:1965-1969 |
| publikationsjahr_sort | 1967 |
| publikationsort | New York, NY [u.a.] |
| publisher | Wiley-Blackwell |
| reference | 69 (1967), S. 155-168 |
| schlagwort | Life and Medical Sciences Cell & Developmental Biology |
| search_space | articles |
| shingle_author_1 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| shingle_author_2 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| shingle_author_3 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| shingle_author_4 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. |
| shingle_catch_all_1 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. Life and Medical Sciences Cell & Developmental Biology Life and Medical Sciences Cell & Developmental Biology Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells. 0021-9541 00219541 Wiley-Blackwell |
| shingle_catch_all_2 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. Life and Medical Sciences Cell & Developmental Biology Life and Medical Sciences Cell & Developmental Biology Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells. 0021-9541 00219541 Wiley-Blackwell |
| shingle_catch_all_3 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. Life and Medical Sciences Cell & Developmental Biology Life and Medical Sciences Cell & Developmental Biology Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells. 0021-9541 00219541 Wiley-Blackwell |
| shingle_catch_all_4 | Brooks, D. E. Millar, J. S. Seaman, G. V. F. Vassar, P. S. Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. Life and Medical Sciences Cell & Developmental Biology Life and Medical Sciences Cell & Developmental Biology Colloidal stability theory is discussed to accomodate the conditions imposed by biological systems. It is shown that to obtain potential curves with secondary minima, Hamaker's constant must be in the range of 1-5 × 10-14 ergs. The effect of increasing the dielectric constant is shown in theory to lower the surface potential and electrophoretic mobility but to increase the total energy of interaction. Calculations made from the theory predict the forces between model cells to be ca. 4.0 × 10-7 dynes.By cone-plate shearing of cell aggregates, the most successful of several techniques tried and discussed, at shear rates approaching 1 × 10-4 second-1 (1.5 × 10-4 dynes) semi-complete disaggregation was achieved although cell disruption was apparent; analysis of blood viscosity data indicates 5-10 × 10-7 dynes are required to separate red cells suspended in plasma. Colloidal stability theory, while not applicable to cell systems associated by special areas of attachment, seems to describe the physicochemical interaction of freely moving or reversibly adherent cells. 0021-9541 00219541 Wiley-Blackwell |
| shingle_title_1 | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| shingle_title_2 | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| shingle_title_3 | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| shingle_title_4 | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Wiley InterScience Backfile Collection 1832-2000 |
| timestamp | 2024-05-06T10:16:43.890Z |
| titel | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| titel_suche | Some physicochemical factors relevant to cellular interactionsThis work was supported by a grant from the National Cancer Institute of Canada and the National Research Council of Canada. |
| topic | W WW-YZ |
| uid | nat_lic_papers_NLM160756898 |