In vitro degradation of a poly(ether urethane) by trypsin
| ISSN: |
0021-9304
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|---|---|
| Keywords: |
Chemistry ; Polymer and Materials Science
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| Source: |
Wiley InterScience Backfile Collection 1832-2000
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| Topics: |
Medicine
Technology
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| Notes: |
In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages.
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| Additional Material: |
7 Ill.
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| Type of Medium: |
Electronic Resource
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| URL: |
| _version_ | 1798297984783351808 |
|---|---|
| addmaterial | 7 Ill. |
| autor | Bouvier, M. Chawla, A. S. Hinberg, I. |
| autorsonst | Bouvier, M. Chawla, A. S. Hinberg, I. |
| book_url | http://dx.doi.org/10.1002/jbm.820250607 |
| datenlieferant | nat_lic_papers |
| hauptsatz | hsatz_simple |
| identnr | NLM160186897 |
| iqvoc_descriptor_keyword | iqvoc_00000092:Materials |
| issn | 0021-9304 |
| journal_name | Journal of Biomedical Materials Research |
| materialart | 1 |
| notes | In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages. |
| package_name | Wiley-Blackwell |
| publikationsjahr_anzeige | 1991 |
| publikationsjahr_facette | 1991 |
| publikationsjahr_intervall | 8009:1990-1994 |
| publikationsjahr_sort | 1991 |
| publikationsort | Hoboken, NJ |
| publisher | Wiley-Blackwell |
| reference | 25 (1991), S. 773-789 |
| schlagwort | Chemistry Polymer and Materials Science |
| search_space | articles |
| shingle_author_1 | Bouvier, M. Chawla, A. S. Hinberg, I. |
| shingle_author_2 | Bouvier, M. Chawla, A. S. Hinberg, I. |
| shingle_author_3 | Bouvier, M. Chawla, A. S. Hinberg, I. |
| shingle_author_4 | Bouvier, M. Chawla, A. S. Hinberg, I. |
| shingle_catch_all_1 | Bouvier, M. Chawla, A. S. Hinberg, I. In vitro degradation of a poly(ether urethane) by trypsin Chemistry Polymer and Materials Science Chemistry Polymer and Materials Science In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages. 0021-9304 00219304 Wiley-Blackwell |
| shingle_catch_all_2 | Bouvier, M. Chawla, A. S. Hinberg, I. In vitro degradation of a poly(ether urethane) by trypsin Chemistry Polymer and Materials Science Chemistry Polymer and Materials Science In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages. 0021-9304 00219304 Wiley-Blackwell |
| shingle_catch_all_3 | Bouvier, M. Chawla, A. S. Hinberg, I. In vitro degradation of a poly(ether urethane) by trypsin Chemistry Polymer and Materials Science Chemistry Polymer and Materials Science In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages. 0021-9304 00219304 Wiley-Blackwell |
| shingle_catch_all_4 | Bouvier, M. Chawla, A. S. Hinberg, I. In vitro degradation of a poly(ether urethane) by trypsin Chemistry Polymer and Materials Science Chemistry Polymer and Materials Science In vitro enzymatic degradation of nonporous films of segmented poly(etherurethane) (Pellethane 2363-80AE) was investigated by incubating the biomaterial in concentrated trypsin solutions for 5 months at room temperature. Chemical degradation of films was monitored by surface analysis techniques such as Fourier transform infrared spectroscopyattenuated total reflectance and electron spectroscopy for chemical analysis. This latter technique proved to be much superior in detecting chemical changes. Extraction of films with methanol and characterization of the extracts by gel permeation chromatography revealed the presence of low-molecular-weight polymers. Results have shown that trypsin has the ability to induce degradation in PEU, the soft segment being most affected, particularly the CH2—O bond of the either linkages. 0021-9304 00219304 Wiley-Blackwell |
| shingle_title_1 | In vitro degradation of a poly(ether urethane) by trypsin |
| shingle_title_2 | In vitro degradation of a poly(ether urethane) by trypsin |
| shingle_title_3 | In vitro degradation of a poly(ether urethane) by trypsin |
| shingle_title_4 | In vitro degradation of a poly(ether urethane) by trypsin |
| sigel_instance_filter | dkfz geomar wilbert ipn albert |
| source_archive | Wiley InterScience Backfile Collection 1832-2000 |
| timestamp | 2024-05-06T10:16:41.256Z |
| titel | In vitro degradation of a poly(ether urethane) by trypsin |
| titel_suche | In vitro degradation of a poly(ether urethane) by trypsin |
| topic | WW-YZ ZG |
| uid | nat_lic_papers_NLM160186897 |