Transcriptional regulation of the Saccharomyces cerevisiae HXK1, HXK2 and GLK1 genes
Herrero, P. ; Galíndez, J. ; Ruiz, N. ; Martínez-Campa, C. ; Moreno, F.
New York, NY [u.a.] : Wiley-Blackwell
Published 1995
New York, NY [u.a.] : Wiley-Blackwell
Published 1995
| ISSN: |
0749-503X
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|---|---|
| Keywords: |
Saccharomyces cerevisiae ; HXK1 ; HXK2 ; GLK1 ; mRNA ; transcriptional control ; Life and Medical Sciences ; Genetics
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| Source: |
Wiley InterScience Backfile Collection 1832-2000
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| Topics: |
Biology
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| Notes: |
In Saccharomyces cerevisiae, the transcriptional regulation of most glycolytic genes has been extensively studied. By contrast, little is known about the transcriptional control of the three glucose-phosphorylating enzymes, although this catalytic reaction has an important role in the regulation of cell metabolism. In this paper, we describe the transcriptional regulation of the HXK1, HXK2 and GLK1 genes in the hope of revealing differences in the steady-state levels of mRNA associated with a particular carbon source used in the culture medium. Our results provide evidence supporting a differential expression of the three genes depending on the carbon source used for growth. We have also studied the induction and repression kinetics of mRNA expression for the HXK1, HXK2 and GLK1 genes.
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| Additional Material: |
4 Ill.
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| Type of Medium: |
Electronic Resource
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| URL: |