High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology]
Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman
National Academy of Sciences
Published 2018
National Academy of Sciences
Published 2018
| Publication Date: |
2018-10-17
|
|---|---|
| Publisher: |
National Academy of Sciences
|
| Print ISSN: |
0027-8424
|
| Electronic ISSN: |
1091-6490
|
| Topics: |
Biology
Medicine
Natural Sciences in General
|
| Published by: |
| _version_ | 1836399069763731456 |
|---|---|
| autor | Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman |
| beschreibung | Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how 〉100... |
| citation_standardnr | 6345556 |
| datenlieferant | ipn_articles |
| feed_id | 113 |
| feed_publisher | National Academy of Sciences |
| feed_publisher_url | http://www.nasonline.org/ |
| insertion_date | 2018-10-17 |
| journaleissn | 1091-6490 |
| journalissn | 0027-8424 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | National Academy of Sciences |
| quelle | PNAS - Proceedings of the National Academy of Sciences |
| relation | http://www.pnas.org/content/115/42/E9944.short?rss=1 |
| search_space | articles |
| shingle_author_1 | Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman |
| shingle_author_2 | Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman |
| shingle_author_3 | Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman |
| shingle_author_4 | Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman |
| shingle_catch_all_1 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how >100... Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_2 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how >100... Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_3 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how >100... Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_4 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify nanoparticles that deliver functional mRNA to cells in vivo. Here we report a system capable of simultaneously quantifying how >100... Cory D. Sago, Melissa P. Lokugamage, Kalina Paunovska, Daryll A. Vanover, Christopher M. Monaco, Nirav N. Shah, Marielena Gamboa Castro, Shannon E. Anderson, Tobi G. Rudoltz, Gwyneth N. Lando, Pooja Mummilal Tiwari, Jonathan L. Kirschman, Nick Willett, Young C. Jang, Philip J. Santangelo, Anton V. Bryksin, James E. Dahlman National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_title_1 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| shingle_title_2 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| shingle_title_3 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| shingle_title_4 | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| timestamp | 2025-06-30T23:37:06.792Z |
| titel | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| titel_suche | High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing [Pharmacology] |
| topic | W WW-YZ TA-TD |
| uid | ipn_articles_6345556 |