Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation]
Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler
National Academy of Sciences
Published 2018
National Academy of Sciences
Published 2018
| Publication Date: |
2018-09-12
|
|---|---|
| Publisher: |
National Academy of Sciences
|
| Print ISSN: |
0027-8424
|
| Electronic ISSN: |
1091-6490
|
| Topics: |
Biology
Medicine
Natural Sciences in General
|
| Published by: |
| _version_ | 1836399049887973376 |
|---|---|
| autor | Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler |
| beschreibung | Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of costimulatory molecules, and cytokine secretion, leading to activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs). Here we screened a synthetic library of 100,000 compounds for innate immune activators using TNF production... |
| citation_standardnr | 6331324 |
| datenlieferant | ipn_articles |
| feed_id | 113 |
| feed_publisher | National Academy of Sciences |
| feed_publisher_url | http://www.nasonline.org/ |
| insertion_date | 2018-09-12 |
| journaleissn | 1091-6490 |
| journalissn | 0027-8424 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | National Academy of Sciences |
| quelle | PNAS - Proceedings of the National Academy of Sciences |
| relation | http://www.pnas.org/content/115/37/E8698.short?rss=1 |
| search_space | articles |
| shingle_author_1 | Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler |
| shingle_author_2 | Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler |
| shingle_author_3 | Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler |
| shingle_author_4 | Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler |
| shingle_catch_all_1 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of costimulatory molecules, and cytokine secretion, leading to activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs). Here we screened a synthetic library of 100,000 compounds for innate immune activators using TNF production... Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_2 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of costimulatory molecules, and cytokine secretion, leading to activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs). Here we screened a synthetic library of 100,000 compounds for innate immune activators using TNF production... Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_3 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of costimulatory molecules, and cytokine secretion, leading to activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs). Here we screened a synthetic library of 100,000 compounds for innate immune activators using TNF production... Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_4 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] Successful cancer immunotherapy entails activation of innate immune receptors to promote dendritic cell (DC) maturation, antigen presentation, up-regulation of costimulatory molecules, and cytokine secretion, leading to activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs). Here we screened a synthetic library of 100,000 compounds for innate immune activators using TNF production... Ying Wang, Lijing Su, Matthew D. Morin, Brian T. Jones, Yuto Mifune, Hexin Shi, Kuan-wen Wang, Xiaoming Zhan, Aijie Liu, Jianhui Wang, Xiaohong Li, Miao Tang, Sara Ludwig, Sara Hildebrand, Kejin Zhou, Daniel J. Siegwart, Eva Marie Y. Moresco, Hong Zhang, Dale L. Boger, Bruce Beutler National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_title_1 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| shingle_title_2 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| shingle_title_3 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| shingle_title_4 | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| timestamp | 2025-06-30T23:36:46.088Z |
| titel | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| titel_suche | Adȷuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice [Immunology and Inflammation] |
| topic | W WW-YZ TA-TD |
| uid | ipn_articles_6331324 |