Mammalian chromosome-telomere length dynamics
| Publication Date: |
2018-07-26
|
|---|---|
| Publisher: |
Royal Society
|
| Electronic ISSN: |
2054-5703
|
| Topics: |
Natural Sciences in General
|
| Keywords: |
genetics, theoretical biology, evolution
|
| Published by: |
| _version_ | 1836399015974928385 |
|---|---|
| autor | Klegarth, A. R., Eisenberg, D. T. A. |
| beschreibung | Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. While the reasons for these associations are unclear, the strength and consistency of the associations across disparate taxa suggest that this is important to telomere biology and should be explored further. If TL is primarily determined by chromosome length, then chromosome length should be considered and controlled for in cross-species analyses of TL. Here, we employ a cross-species approach to explore whether the chromosome length–TL association observed intraspecifically is a determinant of mean TL across species. Data were compiled from two studies characterizing TL across a range of mammalian taxa and analysed in a phylogenetic framework. We found no significant relationship between TL and chromosome size across mammals or within mammalians orders. The pattern trends in the expected direction and we suggest may be masked by evolutionary lag effects. |
| citation_standardnr | 6309717 |
| datenlieferant | ipn_articles |
| feed_id | 220702 |
| feed_publisher | Royal Society |
| feed_publisher_url | http://royalsocietypublishing.org/ |
| insertion_date | 2018-07-26 |
| journaleissn | 2054-5703 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | Royal Society |
| quelle | Royal Society Open Science |
| relation | http://rsos.royalsocietypublishing.org/cgi/content/short/5/7/180492?rss=1 |
| schlagwort | genetics, theoretical biology, evolution |
| search_space | articles |
| shingle_author_1 | Klegarth, A. R., Eisenberg, D. T. A. |
| shingle_author_2 | Klegarth, A. R., Eisenberg, D. T. A. |
| shingle_author_3 | Klegarth, A. R., Eisenberg, D. T. A. |
| shingle_author_4 | Klegarth, A. R., Eisenberg, D. T. A. |
| shingle_catch_all_1 | Mammalian chromosome-telomere length dynamics genetics, theoretical biology, evolution Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. While the reasons for these associations are unclear, the strength and consistency of the associations across disparate taxa suggest that this is important to telomere biology and should be explored further. If TL is primarily determined by chromosome length, then chromosome length should be considered and controlled for in cross-species analyses of TL. Here, we employ a cross-species approach to explore whether the chromosome length–TL association observed intraspecifically is a determinant of mean TL across species. Data were compiled from two studies characterizing TL across a range of mammalian taxa and analysed in a phylogenetic framework. We found no significant relationship between TL and chromosome size across mammals or within mammalians orders. The pattern trends in the expected direction and we suggest may be masked by evolutionary lag effects. Klegarth, A. R., Eisenberg, D. T. A. Royal Society 2054-5703 20545703 |
| shingle_catch_all_2 | Mammalian chromosome-telomere length dynamics genetics, theoretical biology, evolution Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. While the reasons for these associations are unclear, the strength and consistency of the associations across disparate taxa suggest that this is important to telomere biology and should be explored further. If TL is primarily determined by chromosome length, then chromosome length should be considered and controlled for in cross-species analyses of TL. Here, we employ a cross-species approach to explore whether the chromosome length–TL association observed intraspecifically is a determinant of mean TL across species. Data were compiled from two studies characterizing TL across a range of mammalian taxa and analysed in a phylogenetic framework. We found no significant relationship between TL and chromosome size across mammals or within mammalians orders. The pattern trends in the expected direction and we suggest may be masked by evolutionary lag effects. Klegarth, A. R., Eisenberg, D. T. A. Royal Society 2054-5703 20545703 |
| shingle_catch_all_3 | Mammalian chromosome-telomere length dynamics genetics, theoretical biology, evolution Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. While the reasons for these associations are unclear, the strength and consistency of the associations across disparate taxa suggest that this is important to telomere biology and should be explored further. If TL is primarily determined by chromosome length, then chromosome length should be considered and controlled for in cross-species analyses of TL. Here, we employ a cross-species approach to explore whether the chromosome length–TL association observed intraspecifically is a determinant of mean TL across species. Data were compiled from two studies characterizing TL across a range of mammalian taxa and analysed in a phylogenetic framework. We found no significant relationship between TL and chromosome size across mammals or within mammalians orders. The pattern trends in the expected direction and we suggest may be masked by evolutionary lag effects. Klegarth, A. R., Eisenberg, D. T. A. Royal Society 2054-5703 20545703 |
| shingle_catch_all_4 | Mammalian chromosome-telomere length dynamics genetics, theoretical biology, evolution Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. While the reasons for these associations are unclear, the strength and consistency of the associations across disparate taxa suggest that this is important to telomere biology and should be explored further. If TL is primarily determined by chromosome length, then chromosome length should be considered and controlled for in cross-species analyses of TL. Here, we employ a cross-species approach to explore whether the chromosome length–TL association observed intraspecifically is a determinant of mean TL across species. Data were compiled from two studies characterizing TL across a range of mammalian taxa and analysed in a phylogenetic framework. We found no significant relationship between TL and chromosome size across mammals or within mammalians orders. The pattern trends in the expected direction and we suggest may be masked by evolutionary lag effects. Klegarth, A. R., Eisenberg, D. T. A. Royal Society 2054-5703 20545703 |
| shingle_title_1 | Mammalian chromosome-telomere length dynamics |
| shingle_title_2 | Mammalian chromosome-telomere length dynamics |
| shingle_title_3 | Mammalian chromosome-telomere length dynamics |
| shingle_title_4 | Mammalian chromosome-telomere length dynamics |
| timestamp | 2025-06-30T23:36:13.575Z |
| titel | Mammalian chromosome-telomere length dynamics |
| titel_suche | Mammalian chromosome-telomere length dynamics |
| topic | TA-TD |
| uid | ipn_articles_6309717 |