A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA
Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr.
Nature Publishing Group (NPG)
Published 2018
Nature Publishing Group (NPG)
Published 2018
Publication Date: |
2018-07-11
|
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Publisher: |
Nature Publishing Group (NPG)
|
Electronic ISSN: |
2041-1723
|
Topics: |
Biology
Chemistry and Pharmacology
Natural Sciences in General
Physics
|
Published by: |
_version_ | 1836399002121142274 |
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autor | Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. |
beschreibung | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA, Published online: 10 July 2018; doi:10.1038/s41467-018-04704-9 Broadly neutralizing antibodies are potential therapeutics and can aid rational vaccine development. Here, the authors show that the human monoclonal antibody H3v-47 recognizes a highly conserved epitope in HA of H3N2 viruses, inhibits virus replication by blocking egress and other mechanisms, and protects mice from disease. |
citation_standardnr | 6301988 |
datenlieferant | ipn_articles |
feed_id | 134647 |
feed_publisher | Nature Publishing Group (NPG) |
feed_publisher_url | http://www.nature.com/ |
insertion_date | 2018-07-11 |
journaleissn | 2041-1723 |
publikationsjahr_anzeige | 2018 |
publikationsjahr_facette | 2018 |
publikationsjahr_intervall | 7984:2015-2019 |
publikationsjahr_sort | 2018 |
publisher | Nature Publishing Group (NPG) |
quelle | Nature Communications |
relation | http://feeds.nature.com/~r/ncomms/rss/current/~3/_ss5lTZDvr4/s41467-018-04704-9 |
search_space | articles |
shingle_author_1 | Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. |
shingle_author_2 | Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. |
shingle_author_3 | Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. |
shingle_author_4 | Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. |
shingle_catch_all_1 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA, Published online: 10 July 2018; doi:10.1038/s41467-018-04704-9 Broadly neutralizing antibodies are potential therapeutics and can aid rational vaccine development. Here, the authors show that the human monoclonal antibody H3v-47 recognizes a highly conserved epitope in HA of H3N2 viruses, inhibits virus replication by blocking egress and other mechanisms, and protects mice from disease. Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. Nature Publishing Group (NPG) 2041-1723 20411723 |
shingle_catch_all_2 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA, Published online: 10 July 2018; doi:10.1038/s41467-018-04704-9 Broadly neutralizing antibodies are potential therapeutics and can aid rational vaccine development. Here, the authors show that the human monoclonal antibody H3v-47 recognizes a highly conserved epitope in HA of H3N2 viruses, inhibits virus replication by blocking egress and other mechanisms, and protects mice from disease. Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. Nature Publishing Group (NPG) 2041-1723 20411723 |
shingle_catch_all_3 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA, Published online: 10 July 2018; doi:10.1038/s41467-018-04704-9 Broadly neutralizing antibodies are potential therapeutics and can aid rational vaccine development. Here, the authors show that the human monoclonal antibody H3v-47 recognizes a highly conserved epitope in HA of H3N2 viruses, inhibits virus replication by blocking egress and other mechanisms, and protects mice from disease. Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. Nature Publishing Group (NPG) 2041-1723 20411723 |
shingle_catch_all_4 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA, Published online: 10 July 2018; doi:10.1038/s41467-018-04704-9 Broadly neutralizing antibodies are potential therapeutics and can aid rational vaccine development. Here, the authors show that the human monoclonal antibody H3v-47 recognizes a highly conserved epitope in HA of H3N2 viruses, inhibits virus replication by blocking egress and other mechanisms, and protects mice from disease. Sandhya Bangaru; Heng Zhang; Iuliia M. Gilchuk; Thomas G. Voss; Ryan P. Irving; Pavlo Gilchuk; Pranathi Matta; Xueyong Zhu; Shanshan Lang; Travis Nieusma; Juergen A. Richt; Randy A. Albrecht; Hillary A. Vanderven; Robin Bombardi; Stephen J. Kent; Andrew B. Ward; Ian A. Wilson; James E. Crowe Jr. Nature Publishing Group (NPG) 2041-1723 20411723 |
shingle_title_1 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
shingle_title_2 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
shingle_title_3 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
shingle_title_4 | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
timestamp | 2025-06-30T23:36:02.657Z |
titel | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
titel_suche | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA |
topic | W V TA-TD U |
uid | ipn_articles_6301988 |