PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences]
David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet
National Academy of Sciences
Published 2018
National Academy of Sciences
Published 2018
| Publication Date: |
2018-06-20
|
|---|---|
| Publisher: |
National Academy of Sciences
|
| Print ISSN: |
0027-8424
|
| Electronic ISSN: |
1091-6490
|
| Topics: |
Biology
Medicine
Natural Sciences in General
|
| Published by: |
| _version_ | 1836398979017867265 |
|---|---|
| autor | David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet |
| beschreibung | The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we show that pleckstrin homology domain-interacting... |
| citation_standardnr | 6288254 |
| datenlieferant | ipn_articles |
| feed_id | 113 |
| feed_publisher | National Academy of Sciences |
| feed_publisher_url | http://www.nasonline.org/ |
| insertion_date | 2018-06-20 |
| journaleissn | 1091-6490 |
| journalissn | 0027-8424 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | National Academy of Sciences |
| quelle | PNAS - Proceedings of the National Academy of Sciences |
| relation | http://www.pnas.org/content/115/25/E5766.short?rss=1 |
| search_space | articles |
| shingle_author_1 | David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet |
| shingle_author_2 | David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet |
| shingle_author_3 | David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet |
| shingle_author_4 | David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet |
| shingle_catch_all_1 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we show that pleckstrin homology domain-interacting... David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_2 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we show that pleckstrin homology domain-interacting... David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_3 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we show that pleckstrin homology domain-interacting... David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_catch_all_4 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] The identification and targeting of key molecular drivers of melanoma and breast and lung cancer have substantially improved their therapy. However, subtypes of each of these three common, lethal solid tumors lack identified molecular drivers, and are thus not amenable to targeted therapies. Here we show that pleckstrin homology domain-interacting... David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, Mohammed Kashani-Sabet National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
| shingle_title_1 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| shingle_title_2 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| shingle_title_3 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| shingle_title_4 | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| timestamp | 2025-06-30T23:35:40.703Z |
| titel | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| titel_suche | PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer [Medical Sciences] |
| topic | W WW-YZ TA-TD |
| uid | ipn_articles_6288254 |