Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms

Publication Date:
2018-05-17
Publisher:
American Association for the Advancement of Science (AAAS)
Electronic ISSN:
2375-2548
Topics:
Natural Sciences in General
Published by:
http://www.aaas.org/
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autor Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
beschreibung Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the physiological underpinnings for how diatoms survive in chronically iron-limited waters and outcompete other phytoplankton when iron becomes available are unresolved. We show that some diatoms can use siderophore-bound iron, and exhibit a species-specific recognition for siderophore types. In Phaeodactylum tricornutum , hydroxamate siderophores are taken up without previous reduction by a high-affinity mechanism that involves binding to the cell surface followed by endocytosis-mediated uptake and delivery to the chloroplast. The affinity recorded is the highest ever described for an iron transport system in any eukaryotic cell. Collectively, our observations suggest that there are likely a variety of iron uptake mechanisms in diatoms besides the well-established reductive mechanism. We show that iron starvation–induced protein 1 (ISIP1) plays an important role in the uptake of siderophores, and through bioinformatics analyses we deduce that this protein is largely diatom-specific. We quantify expression of ISIP1 in the global ocean by querying the Tara Oceans atlas of eukaryotic genes and show a link between the abundance and distribution of diatom-associated ISIP1 with ocean provinces defined by chronic iron starvation.
citation_standardnr 6260611
datenlieferant ipn_articles
feed_id 228416
feed_publisher American Association for the Advancement of Science (AAAS)
feed_publisher_url http://www.aaas.org/
insertion_date 2018-05-17
journaleissn 2375-2548
publikationsjahr_anzeige 2018
publikationsjahr_facette 2018
publikationsjahr_intervall 7984:2015-2019
publikationsjahr_sort 2018
publisher American Association for the Advancement of Science (AAAS)
quelle Science Advances
relation http://advances.sciencemag.org/cgi/content/short/4/5/eaar4536?rss=1
search_space articles
shingle_author_1 Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
shingle_author_2 Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
shingle_author_3 Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
shingle_author_4 Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
shingle_catch_all_1 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the physiological underpinnings for how diatoms survive in chronically iron-limited waters and outcompete other phytoplankton when iron becomes available are unresolved. We show that some diatoms can use siderophore-bound iron, and exhibit a species-specific recognition for siderophore types. In Phaeodactylum tricornutum , hydroxamate siderophores are taken up without previous reduction by a high-affinity mechanism that involves binding to the cell surface followed by endocytosis-mediated uptake and delivery to the chloroplast. The affinity recorded is the highest ever described for an iron transport system in any eukaryotic cell. Collectively, our observations suggest that there are likely a variety of iron uptake mechanisms in diatoms besides the well-established reductive mechanism. We show that iron starvation–induced protein 1 (ISIP1) plays an important role in the uptake of siderophores, and through bioinformatics analyses we deduce that this protein is largely diatom-specific. We quantify expression of ISIP1 in the global ocean by querying the Tara Oceans atlas of eukaryotic genes and show a link between the abundance and distribution of diatom-associated ISIP1 with ocean provinces defined by chronic iron starvation.
Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
American Association for the Advancement of Science (AAAS)
2375-2548
23752548
shingle_catch_all_2 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the physiological underpinnings for how diatoms survive in chronically iron-limited waters and outcompete other phytoplankton when iron becomes available are unresolved. We show that some diatoms can use siderophore-bound iron, and exhibit a species-specific recognition for siderophore types. In Phaeodactylum tricornutum , hydroxamate siderophores are taken up without previous reduction by a high-affinity mechanism that involves binding to the cell surface followed by endocytosis-mediated uptake and delivery to the chloroplast. The affinity recorded is the highest ever described for an iron transport system in any eukaryotic cell. Collectively, our observations suggest that there are likely a variety of iron uptake mechanisms in diatoms besides the well-established reductive mechanism. We show that iron starvation–induced protein 1 (ISIP1) plays an important role in the uptake of siderophores, and through bioinformatics analyses we deduce that this protein is largely diatom-specific. We quantify expression of ISIP1 in the global ocean by querying the Tara Oceans atlas of eukaryotic genes and show a link between the abundance and distribution of diatom-associated ISIP1 with ocean provinces defined by chronic iron starvation.
Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
American Association for the Advancement of Science (AAAS)
2375-2548
23752548
shingle_catch_all_3 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the physiological underpinnings for how diatoms survive in chronically iron-limited waters and outcompete other phytoplankton when iron becomes available are unresolved. We show that some diatoms can use siderophore-bound iron, and exhibit a species-specific recognition for siderophore types. In Phaeodactylum tricornutum , hydroxamate siderophores are taken up without previous reduction by a high-affinity mechanism that involves binding to the cell surface followed by endocytosis-mediated uptake and delivery to the chloroplast. The affinity recorded is the highest ever described for an iron transport system in any eukaryotic cell. Collectively, our observations suggest that there are likely a variety of iron uptake mechanisms in diatoms besides the well-established reductive mechanism. We show that iron starvation–induced protein 1 (ISIP1) plays an important role in the uptake of siderophores, and through bioinformatics analyses we deduce that this protein is largely diatom-specific. We quantify expression of ISIP1 in the global ocean by querying the Tara Oceans atlas of eukaryotic genes and show a link between the abundance and distribution of diatom-associated ISIP1 with ocean provinces defined by chronic iron starvation.
Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
American Association for the Advancement of Science (AAAS)
2375-2548
23752548
shingle_catch_all_4 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
Phytoplankton growth is limited in vast oceanic regions by the low bioavailability of iron. Iron fertilization often results in diatom blooms, yet the physiological underpinnings for how diatoms survive in chronically iron-limited waters and outcompete other phytoplankton when iron becomes available are unresolved. We show that some diatoms can use siderophore-bound iron, and exhibit a species-specific recognition for siderophore types. In Phaeodactylum tricornutum , hydroxamate siderophores are taken up without previous reduction by a high-affinity mechanism that involves binding to the cell surface followed by endocytosis-mediated uptake and delivery to the chloroplast. The affinity recorded is the highest ever described for an iron transport system in any eukaryotic cell. Collectively, our observations suggest that there are likely a variety of iron uptake mechanisms in diatoms besides the well-established reductive mechanism. We show that iron starvation–induced protein 1 (ISIP1) plays an important role in the uptake of siderophores, and through bioinformatics analyses we deduce that this protein is largely diatom-specific. We quantify expression of ISIP1 in the global ocean by querying the Tara Oceans atlas of eukaryotic genes and show a link between the abundance and distribution of diatom-associated ISIP1 with ocean provinces defined by chronic iron starvation.
Kazamia, E., Sutak, R., Paz-Yepes, J., Dorrell, R. G., Vieira, F. R. J., Mach, J., Morrissey, J., Leon, S., Lam, F., Pelletier, E., Camadro, J.-M., Bowler, C., Lesuisse, E.
American Association for the Advancement of Science (AAAS)
2375-2548
23752548
shingle_title_1 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
shingle_title_2 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
shingle_title_3 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
shingle_title_4 Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
timestamp 2025-06-30T23:34:56.614Z
titel Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
titel_suche Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms
topic TA-TD
uid ipn_articles_6260611