3D printing of a wearable personalized oral delivery device: A first-in-human study
Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C.
American Association for the Advancement of Science (AAAS)
Published 2018
American Association for the Advancement of Science (AAAS)
Published 2018
| Publication Date: |
2018-05-10
|
|---|---|
| Publisher: |
American Association for the Advancement of Science (AAAS)
|
| Electronic ISSN: |
2375-2548
|
| Topics: |
Natural Sciences in General
|
| Published by: |
| _version_ | 1836398925038223360 |
|---|---|
| autor | Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. |
| beschreibung | Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of customizable oral dosage formulations, a U.S. Food and Drug Administration–approved tablet notwithstanding, the full potential of 3D printing in pharmaceutical sciences has not been realized. In particular, 3D-printed drug-eluting devices offer the possibility for personalization in terms of shape, size, and architecture, but their clinical applications have remained relatively unexplored. We used 3D printing to manufacture a tailored oral drug delivery device with customizable design and tunable release rates in the form of a mouthguard and, subsequently, evaluated the performance of this system in the native setting in a first-in-human study. Our proof-of-concept work demonstrates the immense potential of 3D printing as a platform for the development and translation of next-generation drug delivery devices for personalized therapy. |
| citation_standardnr | 6255360 |
| datenlieferant | ipn_articles |
| feed_id | 228416 |
| feed_publisher | American Association for the Advancement of Science (AAAS) |
| feed_publisher_url | http://www.aaas.org/ |
| insertion_date | 2018-05-10 |
| journaleissn | 2375-2548 |
| publikationsjahr_anzeige | 2018 |
| publikationsjahr_facette | 2018 |
| publikationsjahr_intervall | 7984:2015-2019 |
| publikationsjahr_sort | 2018 |
| publisher | American Association for the Advancement of Science (AAAS) |
| quelle | Science Advances |
| relation | http://advances.sciencemag.org/cgi/content/short/4/5/eaat2544?rss=1 |
| search_space | articles |
| shingle_author_1 | Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. |
| shingle_author_2 | Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. |
| shingle_author_3 | Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. |
| shingle_author_4 | Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. |
| shingle_catch_all_1 | 3D printing of a wearable personalized oral delivery device: A first-in-human study Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of customizable oral dosage formulations, a U.S. Food and Drug Administration–approved tablet notwithstanding, the full potential of 3D printing in pharmaceutical sciences has not been realized. In particular, 3D-printed drug-eluting devices offer the possibility for personalization in terms of shape, size, and architecture, but their clinical applications have remained relatively unexplored. We used 3D printing to manufacture a tailored oral drug delivery device with customizable design and tunable release rates in the form of a mouthguard and, subsequently, evaluated the performance of this system in the native setting in a first-in-human study. Our proof-of-concept work demonstrates the immense potential of 3D printing as a platform for the development and translation of next-generation drug delivery devices for personalized therapy. Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. American Association for the Advancement of Science (AAAS) 2375-2548 23752548 |
| shingle_catch_all_2 | 3D printing of a wearable personalized oral delivery device: A first-in-human study Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of customizable oral dosage formulations, a U.S. Food and Drug Administration–approved tablet notwithstanding, the full potential of 3D printing in pharmaceutical sciences has not been realized. In particular, 3D-printed drug-eluting devices offer the possibility for personalization in terms of shape, size, and architecture, but their clinical applications have remained relatively unexplored. We used 3D printing to manufacture a tailored oral drug delivery device with customizable design and tunable release rates in the form of a mouthguard and, subsequently, evaluated the performance of this system in the native setting in a first-in-human study. Our proof-of-concept work demonstrates the immense potential of 3D printing as a platform for the development and translation of next-generation drug delivery devices for personalized therapy. Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. American Association for the Advancement of Science (AAAS) 2375-2548 23752548 |
| shingle_catch_all_3 | 3D printing of a wearable personalized oral delivery device: A first-in-human study Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of customizable oral dosage formulations, a U.S. Food and Drug Administration–approved tablet notwithstanding, the full potential of 3D printing in pharmaceutical sciences has not been realized. In particular, 3D-printed drug-eluting devices offer the possibility for personalization in terms of shape, size, and architecture, but their clinical applications have remained relatively unexplored. We used 3D printing to manufacture a tailored oral drug delivery device with customizable design and tunable release rates in the form of a mouthguard and, subsequently, evaluated the performance of this system in the native setting in a first-in-human study. Our proof-of-concept work demonstrates the immense potential of 3D printing as a platform for the development and translation of next-generation drug delivery devices for personalized therapy. Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. American Association for the Advancement of Science (AAAS) 2375-2548 23752548 |
| shingle_catch_all_4 | 3D printing of a wearable personalized oral delivery device: A first-in-human study Despite the burgeoning interest in three-dimensional (3D) printing for the manufacture of customizable oral dosage formulations, a U.S. Food and Drug Administration–approved tablet notwithstanding, the full potential of 3D printing in pharmaceutical sciences has not been realized. In particular, 3D-printed drug-eluting devices offer the possibility for personalization in terms of shape, size, and architecture, but their clinical applications have remained relatively unexplored. We used 3D printing to manufacture a tailored oral drug delivery device with customizable design and tunable release rates in the form of a mouthguard and, subsequently, evaluated the performance of this system in the native setting in a first-in-human study. Our proof-of-concept work demonstrates the immense potential of 3D printing as a platform for the development and translation of next-generation drug delivery devices for personalized therapy. Liang, K., Carmone, S., Brambilla, D., Leroux, J.-C. American Association for the Advancement of Science (AAAS) 2375-2548 23752548 |
| shingle_title_1 | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| shingle_title_2 | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| shingle_title_3 | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| shingle_title_4 | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| timestamp | 2025-06-30T23:34:49.415Z |
| titel | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| titel_suche | 3D printing of a wearable personalized oral delivery device: A first-in-human study |
| topic | TA-TD |
| uid | ipn_articles_6255360 |