Glucagon contributes to liver zonation [Physiology]
Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada
National Academy of Sciences
Published 2018
National Academy of Sciences
Published 2018
Publication Date: |
2018-04-25
|
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Publisher: |
National Academy of Sciences
|
Print ISSN: |
0027-8424
|
Electronic ISSN: |
1091-6490
|
Topics: |
Biology
Medicine
Natural Sciences in General
|
Published by: |
_version_ | 1836398907978940416 |
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autor | Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada |
beschreibung | Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate that glucagon opposes the actions of Wnt/β-catenin signaling on gene expression... |
citation_standardnr | 6243919 |
datenlieferant | ipn_articles |
feed_id | 113 |
feed_publisher | National Academy of Sciences |
feed_publisher_url | http://www.nasonline.org/ |
insertion_date | 2018-04-25 |
journaleissn | 1091-6490 |
journalissn | 0027-8424 |
publikationsjahr_anzeige | 2018 |
publikationsjahr_facette | 2018 |
publikationsjahr_intervall | 7984:2015-2019 |
publikationsjahr_sort | 2018 |
publisher | National Academy of Sciences |
quelle | PNAS - Proceedings of the National Academy of Sciences |
relation | http://www.pnas.org/content/115/17/E4111.short?rss=1 |
search_space | articles |
shingle_author_1 | Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada |
shingle_author_2 | Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada |
shingle_author_3 | Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada |
shingle_author_4 | Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada |
shingle_catch_all_1 | Glucagon contributes to liver zonation [Physiology] Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate that glucagon opposes the actions of Wnt/β-catenin signaling on gene expression... Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
shingle_catch_all_2 | Glucagon contributes to liver zonation [Physiology] Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate that glucagon opposes the actions of Wnt/β-catenin signaling on gene expression... Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
shingle_catch_all_3 | Glucagon contributes to liver zonation [Physiology] Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate that glucagon opposes the actions of Wnt/β-catenin signaling on gene expression... Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
shingle_catch_all_4 | Glucagon contributes to liver zonation [Physiology] Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal function. Wnt/β-catenin signaling controls metabolic zonation by activating genes in the perivenous hepatocytes, while suppressing genes in the periportal counterparts. We now demonstrate that glucagon opposes the actions of Wnt/β-catenin signaling on gene expression... Xiping Cheng, Sun Y. Kim, Haruka Okamoto, Yurong Xin, George D. Yancopoulos, Andrew J. Murphy, Jesper Gromada National Academy of Sciences 0027-8424 00278424 1091-6490 10916490 |
shingle_title_1 | Glucagon contributes to liver zonation [Physiology] |
shingle_title_2 | Glucagon contributes to liver zonation [Physiology] |
shingle_title_3 | Glucagon contributes to liver zonation [Physiology] |
shingle_title_4 | Glucagon contributes to liver zonation [Physiology] |
timestamp | 2025-06-30T23:34:32.888Z |
titel | Glucagon contributes to liver zonation [Physiology] |
titel_suche | Glucagon contributes to liver zonation [Physiology] |
topic | W WW-YZ TA-TD |
uid | ipn_articles_6243919 |